NINGBO INNO PHARMCHEM CO.,LTD. is pleased to announce the availability of its high-quality Citicoline Sodium powder, a critical pharmaceutical intermediate and nootropic agent widely recognized for its significant benefits in neurological health and cognitive function. As a leading supplier dedicated to providing premium active pharmaceutical ingredients and intermediates, NINGBO INNO PHARMCHEM CO.,LTD. ensures that its Citicoline Sodium meets stringent quality standards required for diverse pharmaceutical applications.

Citicoline Sodium, also known by its other names like Citicoline Sodium Salt or CDP-Choline Sodium, is an endogenous compound of great importance in cellular biochemistry. Chemically, it is Cytidine 5'-(trihydrogen diphosphate) p'-(2-(trimethylammonio)ethyl) ester inner salt monosodium salt, with the CAS registry number 33818-15-4. Its molecular formula is C14H25N4NaO11P2, and it has a molecular weight of 510.31. This compound presents as a white or off-white crystal powder, a form highly suitable for integration into various pharmaceutical formulations. A key characteristic is its excellent solubility in water, which facilitates its use in liquid or solid dosage forms, contrasting with its insolubility in common organic solvents like ethanol, acetone, and chloroform.

The biological significance of Citicoline Sodium stems from its pivotal role in cellular processes, particularly within the brain. It serves as a vital intermediate in the synthesis of phospholipids, which are the fundamental building blocks of cell membranes. By providing the necessary precursors, Citicoline Sodium supports the repair and regeneration of neuronal membranes, a process critical following cellular damage or during aging. Furthermore, it acts as an external source for the synthesis of acetylcholine, a major neurotransmitter involved in learning, memory, and cognitive functions. Its involvement in nucleotide metabolism also underscores its broad impact on cellular health and function.

Functionally, Citicoline Sodium is widely recognized as a brain metabolic activator. It is understood to boost brain cell respiration, enhancing energy production within neurons. By improving cerebral circulation, it ensures adequate oxygen and nutrient supply to brain tissues, which is essential for optimal function and recovery. Its mechanisms also contribute to promoting arousal and potentially reducing cerebrovascular resistance, further benefiting brain health, especially in compromised states.

The clinical applications of Citicoline Sodium are well-documented and continue to be a subject of research. It is frequently used to support recovery and improve consciousness disorders following acute craniocerebral trauma and brain surgery. A significant application is in aiding the gradual restoration of limb function in hemiplegia caused by stroke. Its benefits extend to addressing other functional and conscious disorders resulting from acute central nervous system injury. Moreover, it plays a role in the management of ischemic cerebrovascular disease and vascular dementia, conditions where impaired blood flow and neurodegeneration affect cognitive abilities and motor function. Beyond stroke and injury, Citicoline Sodium has found applications in addressing neurological disorders, supporting patients with Parkinson's disease, and showing promise in managing conditions like glaucoma, where neuroprotective effects are sought.

Quality is paramount for pharmaceutical intermediates. NINGBO INNO PHARMCHEM CO.,LTD. commits to providing Citicoline Sodium that adheres to rigorous quality control protocols. Our product boasts a high purity level of typically ≥98% on a dry basis, ensuring its efficacy and safety for pharmaceutical use. Key specifications include strict limits on impurities such as chlorides, ammonium, iron, phosphate, and other related substances like 5-CMP. Furthermore, solvent residues (methanol, ethanol, acetone), heavy metals, arsenic, and endotoxin levels are carefully controlled and tested to meet pharmaceutical grade requirements. Appearance, solubility, acid value, clarity and color of solution, and identification tests via chemical reaction, IR, and sodium flame are routinely performed to confirm the product's identity and quality. This meticulous approach ensures that our Citicoline Sodium is suitable for integration into final drug formulations aimed at treating sensitive neurological conditions.

Packaging of Citicoline Sodium from NINGBO INNO PHARMCHEM CO.,LTD. is designed to maintain product integrity and quality during transit and storage. The standard packaging is in paper-drums with two plastic bags inside, typically in 25kg net weight units per drum. Proper storage conditions are crucial for maintaining stability over its two-year shelf life. It should be stored in a well-closed place with constant low temperature and protected from direct sunlight. Adherence to these storage guidelines ensures the product remains potent and pure until ready for use.

NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable manufacturer and supplier of pharmaceutical intermediates. Our expertise in synthesis and quality assurance makes us a preferred partner for pharmaceutical companies worldwide. We understand the critical nature of the raw materials used in drug manufacturing and are committed to excellence at every step. For companies looking to purchase high-quality Citicoline Sodium for their formulations, NINGBO INNO PHARMCHEM CO.,LTD. offers a dependable source.

For information regarding the current price of Citicoline Sodium or to inquire about placing an order to buy this essential intermediate, prospective clients are encouraged to contact NINGBO INNO PHARMCHEM CO.,LTD. Our team is ready to provide detailed specifications, discuss bulk purchase options, and answer any questions regarding the suitability of our Citicoline Sodium for specific pharmaceutical applications. We aim to facilitate a smooth and efficient procurement process, providing clients with the confidence that they are sourcing a high-purity, reliable product from a trusted manufacturer and supplier. Investing in quality raw materials like Citicoline Sodium from NINGBO INNO PHARMCHEM CO.,LTD. is an investment in the efficacy and safety of your final pharmaceutical products, ultimately benefiting patients requiring support for brain health and neurological recovery.