Elamipretide, widely recognized by its synonyms such as SS-31, MTP-131, and Bendavia, represents a significant compound in peptide research. This material is a small, synthetic peptide composed of just four amino acids, including one unnatural residue. It has garnered considerable attention for its unique biological properties and potential therapeutic applications, primarily focused on enhancing and protecting mitochondrial function within cells.

Scientifically identified by CAS No. 736992-21-5, Elamipretide possesses a distinct chemical structure: H-d-Arg-dimethylTyr-Lys-Phe-NH2. As a solid material, it typically presents as a fine, white powder. Key quality specifications for Elamipretide powder demand high purity levels, often exceeding 98.0%, with stringent controls on single impurities, bacterial endotoxins (typically less than 30 EU/mg), water content, heavy metals, and residual solvents. Meeting these rigorous standards is crucial for ensuring the material's suitability for various research and potential clinical applications, guaranteeing consistency and reliability.

The primary mechanism of action for Elamipretide involves its targeted interaction with the mitochondrial inner membrane. This selective targeting allows the peptide to exert profound effects on cellular energy production and protection. Research indicates that Elamipretide is highly effective at preventing oxidative damage within cells, including sensitive types like nerve cells. It helps to maintain the integrity of the mitochondrial inner membrane, preventing depolarization, a critical event in cellular dysfunction and programmed cell death (apoptosis). By mitigating these harmful processes, Elamipretide supports overall cellular resilience and health.

Beyond its fundamental protective roles, Elamipretide's positive impact on mitochondrial function translates into promising potential applications. Studies have explored its ability to reduce apoptosis of islet cells and potentially increase islet cell production, which could have significant implications for metabolic health research. Furthermore, it has been observed to potentially improve function following transplantation procedures by protecting donor cells from damage. The potential of Elamipretide as a therapeutic agent is further highlighted by the fact that compounds utilizing it as a main raw material have reportedly advanced into the third phase of clinical trials, indicating a strong potential for future medical use and demonstrating the significance of this peptide in ongoing biomedical research and development.

Obtaining high-quality Elamipretide powder is crucial for ensuring reliable research outcomes and the safety of any potential future applications. Material is typically vacuum-packed in various sizes, from milligrams for laboratory use to grams for larger scale research or formulation development, often shipped with appropriate measures like ice bags to maintain stability. Reliable sourcing from an experienced manufacturer is paramount. For those looking to buy or purchase Elamipretide (SS-31) powder, understanding typical price ranges and finding a trustworthy supplier that adheres to strict quality control standards is essential. Seeking material that meets rigorous quality standards ensures consistency and performance for all research and development needs.