Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
NINGBO INNO PHARMCHEM CO.,LTD. is pleased to offer high-quality Osimertinib Mesylate Powder, a leading active pharmaceutical ingredient (API) crucial in the treatment of non-small cell lung cancer (NSCLC). Osimertinib Mesylate is recognized as a third-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). This API is a white powder with the chemical formula C29H37N7O5S, a molecular weight of 595.719, and a CAS number of 1421373-66-1. Our commitment is to provide pharmaceutical manufacturers with a reliable supply of this essential raw material.
The mechanism of action for Osimertinib Mesylate is highly targeted. It selectively inhibits EGFR sensitive mutations (Ex19del/L858R) and, importantly, the acquired resistance mutation T790M. This selectivity contributes to its efficacy in patients who have developed resistance to earlier generation EGFR TKIs. A significant advantage of Osimertinib Mesylate is its high penetrability to central nervous system (CNS) metastases, making it a valuable option for patients with brain involvement. Furthermore, it demonstrates reduced off-target effects on wild-type EGFR, potentially leading to a better safety profile compared to less selective inhibitors.
Clinical applications for Osimertinib Mesylate are extensive within the NSCLC landscape. It is indicated for the first-line treatment of EGFR Ex19del or L858R mutation positive advanced NSCLC. It is also approved for the treatment of EGFR T790M mutation positive locally advanced or metastatic NSCLC, particularly after progression on previous EGFR TKI therapy. Emerging evidence supports its use as adjuvant therapy for EGFR mutation positive NSCLC after complete resection, aiming to reduce recurrence risk. Exploratory uses include treating CNS metastasis, rare EGFR mutations (such as G719X, L861Q, S768I), and in combination therapies targeting EGFR and MET amplification.
NINGBO INNO PHARMCHEM CO.,LTD. ensures the quality and purity of Osimertinib Mesylate Powder. It is supplied as a pharmaceutical grade powder with an assay typically above 99% as confirmed by HPLC. Our production capacity is substantial, capable of meeting large-scale demands from pharmaceutical companies globally. The material is carefully transported and packaged to maintain its integrity and quality until it reaches the customer.
For pharmaceutical companies looking to source high-quality Osimertinib Mesylate Powder API, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted partner. We offer competitive pricing and reliable supply chain management. If you are looking to buy Osimertinib Mesylate powder or need information on the current Osimertinib Mesylate price, please contact us directly. As a dedicated API supplier and manufacturer, we are ready to discuss your specific needs and provide details for bulk purchase. We aim to be your preferred Osimertinib Mesylate manufacturer.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
