Sarpogrelate Hydrochloride, identified by its CAS number 135159-51-2, is a significant active pharmaceutical ingredient (API) widely recognized for its therapeutic efficacy. As a key component in pharmaceutical formulations, this compound plays a vital role in the treatment of specific medical conditions, particularly those related to vascular health.

Chemically, Sarpogrelate Hydrochloride presents as a white crystalline powder. This solid form ensures stability and ease of handling during various stages of pharmaceutical processing. Its high purity, typically exceeding 99%, is a critical attribute, guaranteeing its suitability for medicinal use and compliance with stringent pharmaceutical standards. The compound functions primarily as a selective antagonist of the serotonin 5-HT2A receptor. By blocking these receptors, it helps to inhibit platelet aggregation and counteract vasoconstriction, two crucial factors in the development and progression of certain cardiovascular and peripheral vascular disorders.

The primary application of Sarpogrelate Hydrochloride lies in its use for treating symptoms associated with chronic arterial occlusion, such as peripheral artery disease. It helps to improve blood flow and alleviate pain caused by insufficient circulation, thereby enhancing the quality of life for patients. Its mechanism of action targeting the 5-HT2A receptor makes it a valuable therapeutic agent in managing conditions where excessive platelet activation and vascular smooth muscle contraction contribute to pathology. Research has also explored its potential in other areas related to its anti-platelet and vasodilator properties.

As a medicine grade material, Sarpogrelate Hydrochloride 135159-51-2 meets the rigorous quality control requirements essential for pharmaceutical manufacturing. Its consistent quality and defined specifications ensure reliable performance in the production of finished drug products. Sourcing a high-quality API is paramount for pharmaceutical companies to ensure the safety and efficacy of their medications.

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