Hydrolyzed Chondroitin Sulfate Oligosaccharide (HCSO) represents a significant advancement in joint health supplements. This cutting-edge ingredient is derived from high-quality chondroitin sulfate, typically sourced from marine cartilage, through a meticulous bioenzymatic hydrolysis process. The key differentiator of HCSO lies in its significantly reduced molecular weight compared to conventional chondroitin sulfate, which translates directly into superior absorption and utilization by the body. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a leading producer of this innovative and highly effective ingredient.

HCSO offers a comprehensive range of benefits crucial for maintaining and restoring joint integrity. It actively promotes cartilage regeneration by supporting the growth and recovery of chondrocytes, the vital cells responsible for cartilage formation. This leads to improved joint function and enhanced flexibility. Furthermore, HCSO is effective in inhibiting the activity of enzymes that degrade cartilage, thereby protecting existing joint structures from damage. Its unique properties also aid in the removal of harmful substances from the joint cavity, which significantly contributes to alleviating joint pain and stiffness. Scientific research highlights HCSO's role in immobilizing minerals in osteocalcin, providing crucial support for overall bone health. Recent studies also underscore HCSO's potent inhibitory activity on osteoclast differentiation and its positive influence on increasing the viability of myoblast cells during myotube differentiation, suggesting broader musculoskeletal advantages.

From a product perspective, Hydrolyzed Chondroitin Sulfate Oligosaccharide is presented as a fine white powder, known for its high water-absorbent nature. It exhibits excellent solubility in water, making it easy to incorporate into various formulations, while remaining insoluble in common organic solvents like ethanol or acetone. Our HCSO boasts exceptional purity, consistently exceeding 90%, and meticulously conforms to USP32 grade specifications, ensuring consistent quality and maximum efficacy. The ultra-low molecular weight, typically averaging around 1 kDa, is a critical factor behind its superior bioavailability, allowing for rapid and efficient absorption into the bloodstream where it can exert its beneficial effects.

The safety profile of HCSO has been rigorously evaluated through comprehensive toxicological assessments. Studies, including bacterial reverse mutation tests, in vitro mammalian cell gene mutation assays, and in vivo mammalian erythrocyte micronucleus assays, have consistently demonstrated that HCSO is non-genotoxic. A robust 90-day repeated-dose oral toxicity study in rats further solidified its remarkable safety. In this study, the No Observed Adverse Effect Level (NOAEL) was determined to be 4,000 mg/kg body weight/day, which was the highest dose tested. These extensive findings unequivocally confirm HCSO's safety and suitability for a wide array of applications in human health.

As a dedicated manufacturer and supplier of high-quality pharmaceutical and nutraceutical ingredients, NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering premium Hydrolyzed Chondroitin Sulfate Oligosaccharide that meets the highest industry standards. For businesses and formulators looking to buy or purchase this advanced ingredient, NINGBO INNO PHARMCHEM CO.,LTD. offers flexible ordering options and competitive price structures, ensuring accessibility for both large-scale production and specialized product development. Our unwavering commitment to stringent quality control, technical support, and customer satisfaction makes us a reliable supplier for all your Hydrolyzed Chondroitin Sulfate Oligosaccharide requirements. Partner with us to leverage the significant health benefits of this superior joint support solution.