Hydroxyectoine, a remarkable naturally occurring compatible solute, stands as a testament to nature's ingenious solutions for survival in extreme environments. It is increasingly recognized for its unparalleled protective capabilities, making it an invaluable asset across diverse industries.

This exceptional extremolyte is a cyclic derivative of aspartate, chemically identified as (4S,5S)-2-methyl-5-hydroxy-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, with a molecular formula of C6H10N2O3 and a molecular weight of 158.16. Typically appearing as a solid with an assay of ≥95%, its unique molecular structure enables it to act as a powerful chemical chaperone, effectively stabilizing biomolecules and entire cells against a multitude of environmental stressors. Hydroxyectoine achieves this by preferentially interacting with water molecules, enhancing their hydrogen bonding network and increasing tetrahedral order, thus safeguarding cellular components from denaturation, aggregation, and damage. It is a strong water-binder, capable of accumulating a significant number of water molecules around itself, maintaining crucial cellular hydration. A key advantage of hydroxyectoine over its precursor, ectoine, is its notably higher glass transition temperature, rendering it a superior protectant against desiccation.

Beyond its role in osmotic regulation, Hydroxyectoine provides robust protection against extreme temperatures (both high and low), freezing, and various forms of oxidative stress, including those induced by UV radiation. Its ability to shield DNA from damage by ionizing radiation and scavenge hydroxyl radicals further underscores its potent cytoprotective effects. This multifaceted defense mechanism makes it a vital compound for organisms thriving in challenging conditions.

The versatile properties of Hydroxyectoine translate into a broad spectrum of practical applications:

• Cosmetics & Skincare: Its exceptional moisturizing and cell-protecting properties have propelled Hydroxyectoine to the forefront of the cosmetic industry. It is widely used in anti-aging formulations, sunscreens, and creams, offering defense against premature photoaging, UV-induced immunosuppression, and general skin damage, leading to healthier, more resilient skin.

• Medicine & Pharmaceuticals: In the medical field, Hydroxyectoine shows promise as a stabilizer for proteins, enzymes, and other biological macromolecules. Research indicates its potential in addressing neurodegenerative diseases, such as Alzheimer's, by inhibiting amyloid aggregation, and in alleviating symptoms of allergic rhinoconjunctivitis. Its capacity to stabilize sensitive biological products, like antibodies in spray-dried or freeze/thaw formulations, highlights its utility in drug development and preservation.

• Biotechnology: Hydroxyectoine serves as an indispensable tool in biotechnology. It stabilizes enzyme activity in vitro, promotes proper protein folding in vivo, and enhances the resistance of cells and DNA to extreme conditions. Its role in maintaining cell membrane integrity and chelating metals broadens its application in various bioprocesses and research. It can also be explored as an additive in biological waste and wastewater treatment systems to improve efficiency under stressful conditions.

The demand for high-purity Hydroxyectoine is steadily increasing, positioning it as a high-value chemical in the global market. While traditionally produced through microbial fermentation, advancements are continuously being made to optimize its synthesis. Our focus is on leveraging cutting-edge biotechnology and fermentation techniques to ensure a consistent supply of superior quality Hydroxyectoine. We are committed to refining production processes, including exploring low-salt fermentation methods, to enhance efficiency and environmental sustainability.

We understand the critical role Hydroxyectoine plays in numerous advanced applications. As a dedicated manufacturer and supplier, we offer Hydroxyectoine that meets stringent quality standards, backed by comprehensive certificates and reports. For those looking to buy or purchase Hydroxyectoine, we ensure good price and reliable delivery. Contact us for quotes and product documentation.