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Ioversol CAS 87771-40-2: An Essential Radiographic Contrast Agent for Advanced Imaging

At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing high-quality chemical compounds that serve critical functions across various industries, especially in healthcare. Among our distinguished offerings, Ioversol CAS 87771-40-2 stands out as a vital component in modern medical diagnostics. This article delves into the properties, mechanism, applications, and advantages of Ioversol, highlighting its significance as a radiographic contrast agent.


Ioversol, chemically known as N,N’-Bis(2,3-dihydroxypropyl)-5-[(2-hydroxyacetyl)-(2-hydroxyethyl)amino]-2,4,6-triiodo-benzene-1,3-dicarboxamide, is a prominent nonionic, water-soluble compound. With a molecular formula of C18H24I3N3O9 and a molecular weight of 807.11, Ioversol is characterized by its white solid appearance and precise physical properties, including a melting point of 180-182°C. Its robust chemical structure ensures stability, critical for its demanding medical applications.


The mechanism of action of Ioversol is rooted in its unique chemical composition, specifically its tri-iodinated benzene derivative structure. Each molecule contains three iodine atoms, elements with a high atomic number (53), which are highly effective at absorbing X-rays. When Ioversol is administered into the body, these iodine atoms absorb X-rays significantly more than surrounding tissues. This differential absorption creates a stark contrast in the resulting images, making internal structures more visible and allowing healthcare professionals to distinguish between normal and abnormal tissues with greater clarity.


A significant advantage of Ioversol over older ionic contrast agents lies in its nonionic nature. Unlike ionic agents that dissociate into charged particles in solution, Ioversol remains undissociated. This property leads to a lower osmolality (a measure of solute concentration) compared to ionic agents, which in turn reduces the likelihood of adverse reactions such as pain, heat sensation, and particularly, nephrotoxicity (kidney damage). This makes Ioversol a safer option for a broader range of patients, including those with compromised kidney function or other pre-existing conditions.


Ioversol finds extensive application in a variety of medical imaging procedures, playing an indispensable role in accurate diagnosis and monitoring. Its primary uses include:

  • Computed Tomography (CT) Scans: Ioversol is widely used to enhance the visibility of blood vessels, organs, and other soft tissues in CT imaging of both the head and body. This helps radiologists identify blockages, abnormalities, tumors, and lesions with enhanced diagnostic accuracy.
  • Angiography: In procedures such as cerebral arteriography, peripheral arteriography, visceral and renal arteriography, aortography, coronary arteriography, and angiocardiography, Ioversol effectively highlights the vascular system. This is crucial for diagnosing conditions like aneurysms, stenosis, and vascular malformations.
  • Urography: Ioversol assists in visualizing the urinary tract, including the kidneys, ureters, and bladder, aiding in the detection of kidney stones, tumors, and structural anomalies.
  • Intravenous Digital Subtraction Angiography (IV-DSA): It also serves in IV-DSA for detailed visualization of blood vessels.

Administered typically via intravenous injection or infusion, Ioversol exhibits a rapid onset of action, with peak contrast effects appearing within minutes. While generally well-tolerated, potential side effects are carefully considered by healthcare professionals during patient screening and monitoring, ensuring optimal patient safety throughout the diagnostic process.


As a dedicated manufacturer and supplier of high-quality chemical compounds, NINGBO INNO PHARMCHEM CO.,LTD. ensures that our Ioversol meets rigorous quality standards. We offer competitive price options for bulk purchase, catering to the needs of pharmaceutical companies and medical institutions worldwide. For those looking to buy Ioversol CAS 87771-40-2, NINGBO INNO PHARMCHEM CO.,LTD. provides reliable supply and comprehensive technical support.


In conclusion, Ioversol is a testament to the advancements in medical imaging, offering unparalleled clarity and safety for diagnostic procedures. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a trusted source for this critical compound, contributing to better healthcare outcomes globally.

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