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Iron is an essential element for life, playing a critical role in oxygen transport, energy metabolism, and DNA synthesis. However, excess iron can be toxic, generating reactive oxygen species that damage cellular components. Conditions like thalassemia major and repeated blood transfusions can lead to a dangerous accumulation of iron in the body, a state known as iron overload. This chronic excess iron can deposit in vital organs, leading to severe dysfunction and potentially life-threatening complications.
Iron chelation therapy is the cornerstone of managing such conditions. Deferoxamine (CAS 70-51-9) stands out as a powerful iron-chelating agent. Its molecular structure is adept at binding strongly to ferric iron (Fe3+), forming a stable, water-soluble complex called ferrioxamine. This complex is then readily excreted from the body, primarily via the kidneys. This mechanism effectively removes excess iron, preventing further tissue damage and alleviating the burden on organs like the heart and liver.
Beyond its direct iron-binding action, research suggests Deferoxamine may also influence other cellular processes, including up-regulating Hypoxia-Inducible Factor 1-alpha (HIF-1α) and inducing apoptosis in certain cells. These properties open avenues for its investigation in various research areas, including cancer therapy and the study of cellular responses to stress. For medical professionals and researchers seeking to buy Deferoxamine, understanding its precise mechanism of action is key to its effective application. As a leading manufacturer and supplier, we ensure that our Deferoxamine meets the high standards required for such critical scientific and medical uses. Our commitment to quality means you can trust us to provide reliable Deferoxamine to support your therapeutic and research goals.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
