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Isobutyl Cinnamate: Chemical Properties, Safety, and Regulatory Compliance

In the realm of flavor and fragrance ingredients, a thorough understanding of a chemical's properties, safety profile, and regulatory standing is paramount. Isobutyl Cinnamate (CAS 122-67-8) is a synthetic aromatic ester widely used for its desirable sensory characteristics. This article provides an overview of its chemical attributes, safety considerations, and compliance information relevant to industry professionals.

Isobutyl Cinnamate is chemically identified as 2-methylpropyl 3-phenylprop-2-enoate. Its molecular formula is C13H16O2, with a molecular weight of 204.26 g/mol. The compound typically presents as a colorless to pale yellow liquid, possessing a distinctively sweet, fruity, and balsamic odor that makes it highly valuable in flavor and fragrance formulations. Key physical properties include a boiling point of approximately 287°C and a flash point above 110°C (TCC), indicating good stability. Its refractive index is typically around 1.54.

From a safety perspective, Isobutyl Cinnamate is generally considered to have low toxicity. According to safety data sheets (SDS), it may cause mild skin irritation and eye irritation (H316, H320) and can be harmful if swallowed (H302). Appropriate handling precautions, such as wearing protective clothing and ensuring adequate ventilation, are recommended. Storage should be in cool, dry conditions in tightly sealed containers, protected from heat and light. For professionals seeking to purchase this chemical, understanding these safety aspects is crucial for responsible handling and formulation.

Regulatory compliance is a critical factor for Isobutyl Cinnamate's application, particularly in food and cosmetic products. It is listed as FEMA GRAS (Generally Recognized As Safe) number 2193 and is approved for use in food by regulatory bodies like the FDA (under 21 CFR 172.515) and EFSA. Its use levels are regulated, with recommendations for cosmetic applications often around 0.5000% in the final product. Manufacturers and suppliers must ensure their product meets these stringent standards, and buyers should verify the regulatory status relevant to their target markets.

The sourcing of Isobutyl Cinnamate from reputable manufacturers and suppliers is vital to ensure both quality and compliance. Companies looking to buy Isobutyl Cinnamate often prioritize those offering high purity (≥98%) and adherence to international quality management systems. Engaging with established suppliers, particularly from regions like China known for robust chemical manufacturing capabilities, can provide access to this essential ingredient with the necessary certifications and documentation, supporting the development of safe and compliant flavor and fragrance products.

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