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While (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione, commonly known by its CAS number 14805-29-9, is prominently recognized as a crucial intermediate for Lurasidone synthesis, its utility in chemical synthesis extends significantly further. This bicyclic imide structure offers a versatile platform for a wide array of advanced organic transformations, making it valuable for researchers and chemists developing novel compounds.
The core functionality of CAS 14805-29-9 lies in its rigid bicyclic framework and the reactive imide group. This combination allows for regioselective and stereoselective modifications, enabling the construction of complex molecular architectures. In pharmaceutical research and development, beyond its role in Lurasidone, it can serve as a precursor for other biologically active molecules. Its structure can be incorporated into various heterocyclic systems or used to introduce specific stereochemical configurations into target compounds.
Chemists often leverage the reactivity of the imide nitrogen for N-alkylation, N-acylation, or reactions with electrophiles, leading to a diverse range of derivatives. The carbonyl groups of the imide can also undergo reduction or nucleophilic attack, providing further avenues for functionalization. For those looking to buy this intermediate for research purposes, understanding its potential chemical transformations is key to unlocking its full synthetic potential. Exploring its use as a scaffold for libraries of compounds in drug discovery is another significant application.
Furthermore, the specific stereochemistry of (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione makes it an attractive chiral building block. Its incorporation into chiral auxiliaries or ligands for asymmetric catalysis is an area of ongoing exploration in synthetic chemistry. Manufacturers and suppliers like NINGBO INNO PHARMCHEM CO.,LTD. provide this intermediate with high purity, ensuring that its inherent structural and stereochemical integrity is maintained for these advanced applications.
In conclusion, while its role in Lurasidone synthesis is well-established, (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione (CAS 14805-29-9) is a powerful tool in the synthetic chemist's arsenal. Its unique structural features and reactivity offer exciting possibilities for innovation across various chemical disciplines. Investigating its diverse applications and securing a reliable supply is a strategic move for any research-oriented organization.
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