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In the complex landscape of pharmaceutical development, the availability of high-quality intermediates is paramount. Among these essential building blocks is 3-(Bromomethyl)-1,2-Difluoro-4-Methoxybenzene, identified by its CAS number 886501-83-3. This compound plays a critical role in the synthesis of Linzagolix, an active pharmaceutical ingredient (API) used in therapeutic applications.
Known by several synonyms including 2-(Bromomethyl)-3,4-Difluoro-1-Methoxybenzene, this intermediate has a molecular formula of C8H7BrF2O and a molecular weight of 237.04 g/mol. It typically presents as a powder, a common form for many chemical intermediates facilitating handling and reaction processes. Key predicted physical properties include a boiling point of approximately 225.9°C and a density around 1.566 g/cm3. Its melting point is reported to be between 46-48°C.
The significance of 3-(Bromomethyl)-1,2-Difluoro-4-Methoxybenzene lies in its specific chemical structure, which incorporates a bromomethyl group and difluoromethoxy substitution on a benzene ring. This unique arrangement makes it a reactive and versatile molecule, essential for introducing specific functionalities required in the later stages of Linzagolix synthesis. Its use ensures the correct formation of the Linzagolix molecule, impacting the final API's efficacy, safety, and purity profile.
Producing pharmaceutical intermediates like CAS 886501-83-3 requires stringent quality control and adherence to industry standards. Purity and consistency are non-negotiable, as even minor impurities in an intermediate can affect the quality of the final API. Therefore, sourcing this compound from a reliable manufacturer committed to high standards is crucial for pharmaceutical companies developing or producing Linzagolix.
For researchers and pharmaceutical companies requiring this specific intermediate, locating a trustworthy supplier is the next step. Availability, lead time, and support documentation (like Certificates of Analysis) are key factors in the procurement process. When considering where to buy or purchase 3-(Bromomethyl)-1,2-Difluoro-4-Methoxybenzene, inquiring about minimum order quantities (MOQ) and lead times is important. Discussions around price are also essential for cost-effective production scaling. Engaging directly with experienced suppliers can provide valuable insights into bulk availability and technical support for synthesis applications.
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