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In the pharmaceutical industry, the quality and availability of chemical intermediates are paramount for successful drug discovery and manufacturing. 1,3-Dimethyl-5-hydroxypyrazole, known by its CAS number 5203-77-0, is a significant pyrazole derivative widely utilized as a building block in organic synthesis, particularly for pharmaceutical applications. Understanding its properties and where to source it reliably is essential for research scientists and procurement specialists.
1,3-Dimethyl-5-hydroxypyrazole is characterized by its crystalline powder appearance, typically white to light yellow. It possesses a melting point in the range of 113-117°C and a boiling point of 226°C, with a pKa value of approximately 9.19. These physical and chemical properties make it a stable and manageable intermediate for various chemical transformations. Its utility in synthesizing complex pharmaceutical compounds highlights its importance in the medicinal chemistry landscape.
When seeking to buy this chemical, focusing on reputable manufacturers and suppliers is crucial. Many businesses turn to China for cost-effective and high-quality chemical intermediates. Suppliers often provide detailed product specifications, including purity levels, synthesis methods, and safety data sheets (SDS). This information is vital for ensuring the intermediate meets the stringent requirements of pharmaceutical production. For instance, knowing the synthesis route, which often involves reacting ethyl acetoacetate with methylhydrazine, can provide insights into potential impurities and quality control measures.
Procurement managers often compare quotes from various suppliers to secure the best price for CAS 5203-77-0. Factors influencing price include batch size, purity, and the supplier's logistical capabilities. Many Chinese chemical manufacturers offer competitive pricing for bulk orders, making them attractive partners for companies requiring significant quantities. Furthermore, efficient shipping arrangements, often through global carriers, ensure timely delivery to laboratories and manufacturing sites worldwide.
In conclusion, 1,3-Dimethyl-5-hydroxypyrazole (CAS 5203-77-0) is an indispensable intermediate for pharmaceutical synthesis. By partnering with reliable suppliers, particularly those with a strong presence in China's chemical market, companies can ensure a consistent supply of high-quality material at competitive prices. This strategic sourcing approach supports efficient R&D and facilitates the successful development of new pharmaceutical products.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
