In the meticulous world of chemical manufacturing and R&D, precise specifications for intermediates are non-negotiable. 2-Chloro-5-hydroxypyridine, identified by CAS number 41288-96-4, is a critical organic synthesis intermediate used in pharmaceuticals, agrochemicals, and specialty chemicals. For procurement professionals and research scientists, knowing the key specifications to look for when you buy 2-chloro-5-hydroxypyridine is fundamental to ensuring the success of your projects.

The Importance of Product Specifications

2-Chloro-5-hydroxypyridine (C5H4ClNO, MW: 129.54) is typically supplied as a white powder. Its value as an intermediate lies in its specific chemical reactivity, enabled by the chlorine and hydroxyl substituents on the pyridine ring. When procuring this chemical, attention to its specifications guarantees that it will perform as expected in synthesis and meet regulatory requirements.

Essential Specifications for Your Purchase

When you are ready to purchase 2-chloro-5-hydroxypyridine, consider the following critical specifications:

• Assay (Purity): This is perhaps the most critical specification. For most applications, particularly in pharmaceuticals and agrochemicals, a high purity level is required. A minimum assay of ≥98.0% is commonly expected. Higher purity grades may be available for highly sensitive applications.
• Appearance: The product should typically be a white powder. Any deviation from this could indicate contamination or degradation.
• Melting Point: While exact melting points can vary slightly, a typical range of 155-158°C (as per some sources) or 168-172°C (as per others) is indicative of purity. A broad melting range can suggest impurities.
• Moisture Content: For stability and accurate weighing, low moisture content is desirable. Suppliers often specify ≤0.5%.
• Impurity Profile: Beyond overall purity, understanding the nature and level of specific impurities is crucial. Reputable suppliers will provide information on total impurities and individual impurity limits (e.g., Total ≤1.0%, Individual ≤0.5%).

Why Source from a Reputable Manufacturer?

When you buy CAS 41288-96-4, partnering with a reputable organic synthesis intermediate supplier, especially one based in China, offers distinct advantages:

• Consistent Quality: Established manufacturers invest in rigorous quality control processes to ensure that each batch meets the specified standards.
• Competitive Pricing: Many Chinese manufacturers offer competitive pricing for high-quality intermediates, making them an attractive option for wholesale purchases.
• Technical Data: They typically provide comprehensive technical documentation, including detailed CoAs and MSDS sheets.

Conclusion

The successful application of 2-Chloro-5-hydroxypyridine hinges on its quality and adherence to specifications. By focusing on the assay, appearance, melting point, and impurity profile when you buy 2-chloro-5-hydroxypyridine, you ensure the reliability of your synthesis processes. Always partner with trusted suppliers who can consistently deliver materials meeting these stringent requirements, ensuring your research and production goals are met effectively.