In the realm of advanced skincare ingredients, Polyhydroxy Acids (PHAs) have gained considerable traction for their efficacy and gentleness. Among the most prominent PHAs are Lactobionic Acid and Gluconolactone, both lauded for their ability to exfoliate, hydrate, and protect the skin. As a manufacturer and supplier specializing in high-quality cosmetic raw materials, we often field questions about which PHA is best suited for specific formulations. This article aims to clarify the distinctions and benefits of both, helping you make an informed choice.
Understanding Polyhydroxy Acids (PHAs)
PHAs represent a newer generation of hydroxy acids compared to Alpha Hydroxy Acids (AHAs). Their primary advantage lies in their larger molecular structure. This means they penetrate the skin more slowly and superficially, resulting in significantly less irritation and a gentler exfoliating experience. They are also known for their humectant (moisturizing) and antioxidant properties.
Lactobionic Acid (CAS 96-82-2): The Antioxidant Powerhouse
Lactobionic Acid is derived from lactose. Its key strengths lie in its powerful antioxidant capabilities and its effectiveness as a humectant. It actively fights free radical damage, which is a major contributor to skin aging. Furthermore, its substantial molecular size allows it to bind water effectively, keeping the skin hydrated and plump. It provides gentle exfoliation, improving skin texture and tone without causing sensitivity.
Key attributes of Lactobionic Acid:
Gluconolactone: The Gentle Hydrator and Exfoliator
Gluconolactone is a milder PHA, often recommended for extremely sensitive or compromised skin. It offers effective exfoliation and significant hydration. While it possesses antioxidant properties, they are generally considered less potent than those of Lactobionic Acid. Its primary benefit is its exceptional gentleness and ability to improve skin barrier function and hydration.
Key attributes of Gluconolactone:
Selecting the Right Ingredient for Your Product
Both Lactobionic Acid and Gluconolactone are valuable ingredients. If your formulation's primary goal is robust antioxidant protection alongside gentle exfoliation and hydration, Lactobionic Acid is an excellent choice. For products specifically targeting extremely sensitive or post-procedure skin that require maximum gentleness and hydration, Gluconolactone might be preferred. As a supplier, we offer high-purity versions of both, ensuring you can buy the best raw materials for your needs.
We encourage you to buy our 98% pure Lactobionic Acid for its advanced anti-aging and antioxidant benefits. As your trusted manufacturer and supplier, we are here to support your product development with high-quality ingredients and expert advice.
Manufacturing Facilities






Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.