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For chemists, R&D scientists, and procurement specialists in the pharmaceutical industry, a deep understanding of an API's chemical profile is fundamental. Letermovir (CAS 917389-32-3) is a complex molecule with specific properties that dictate its handling, storage, and application in antiviral therapies. This article provides a comprehensive look at the chemical characteristics of Letermovir, essential information for sourcing from reliable manufacturers and suppliers.
Letermovir, identified by CAS number 917389-32-3, has the molecular formula C29H28F4N4O4 and a molecular weight of approximately 572.55 g/mol. Structurally, it is a quinazoline derivative featuring fluoro-, methoxy-, and trifluoromethyl-phenyl substituents, along with a piperazine ring and an acetic acid moiety. This intricate structure contributes to its specific biological activity and dictates its chemical behavior. Typically supplied as an off-white to yellow powder, Letermovir exhibits moderate solubility in DMSO and is generally insoluble in water, which is important for formulation considerations. Its stability is maintained under recommended storage conditions (e.g., cool, dry place, desiccated at -20°C).
The synthesis of Letermovir is a multi-step process requiring precise control over reaction conditions and purification techniques to achieve the high purity (>99%) demanded by the pharmaceutical industry. While the detailed synthesis pathways are proprietary to Letermovir manufacturers, common intermediates and reagents are often cited in scientific literature. Ensuring the quality of the final product involves rigorous analytical testing, including High-Performance Liquid Chromatography (HPLC) for purity, Mass Spectrometry (MS) for molecular weight verification, and Nuclear Magnetic Resonance (NMR) for structural confirmation. As a conscientious supplier, we provide detailed COAs to confirm these critical parameters, assuring our clients of the product's integrity.
Proper handling and storage are crucial for maintaining the potency and stability of Letermovir. It is typically stored in sealed, dry containers at low temperatures. Safety data sheets (SDS) provide comprehensive information on potential hazards, such as H361 (May damage fertility or the unborn child) and H373 (May cause damage to organs through prolonged or repeated exposure), along with necessary precautionary measures (P-statements). When you buy Letermovir, always consult the SDS for detailed safety guidelines. Our commitment as a chemical supplier extends to providing all necessary safety information for responsible use.
For researchers and pharmaceutical developers, having access to accurate chemical data and high-quality Letermovir is fundamental. By choosing reputable Letermovir manufacturers and suppliers, such as ourselves, you ensure the integrity of your research and development processes. We offer Letermovir with guaranteed purity and provide comprehensive technical documentation, making us a reliable partner for your chemical sourcing needs.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
