Levofloxacin Hemihydrate, identified by CAS 138199-71-0, stands as a critical active pharmaceutical ingredient (API) in the global healthcare sector. As a third-generation fluoroquinolone antibiotic, it is highly valued for its broad-spectrum antimicrobial activity, making it a powerful tool in combating a wide range of bacterial infections. NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a dedicated supplier of this high-quality compound, ensuring its availability for pharmaceutical manufacturing worldwide.

This advanced antibiotic operates by targeting bacterial DNA gyrase (bacterial topoisomerase II) and topoisomerase IV, essential enzymes for bacterial DNA replication, transcription, repair, and recombination. By inhibiting these enzymes, Levofloxacin Hemihydrate effectively prevents bacterial growth and proliferation, leading to the eradication of the infection. Its mechanism of action grants it strong antibacterial activity against most Enterobacteriaceae bacteria, including Escherichia coli, Klebsiella, Proteus, Salmonella, and Shigella, as well as Gram-negative bacteria such as Haemophilus influenzae, Legionella pneumophila, and Neisseria gonorrhoeae. Furthermore, it demonstrates efficacy against Gram-positive bacteria like Staphylococcus aureus, Streptococcus pneumoniae, and Streptococcus pyogenes, and atypical respiratory pathogens such as Mycoplasma pneumoniae and Chlamydia pneumoniae.

The versatility of Levofloxacin Hemihydrate makes it indispensable in treating a variety of conditions. It is commonly prescribed for respiratory tract infections, including bacterial pneumonia and bronchitis, as well as sinusitis. Its applications extend to skin and soft tissue infections, urinary tract infections (UTIs), kidney infections, and prostate infections (prostatitis). Beyond these common uses, it plays a vital role in the post-exposure treatment of serious conditions like anthrax and plague, often as a key component in combination therapies. Its availability in both oral and injectable formulations further enhances its utility and administration flexibility in clinical settings.

At NINGBO INNO PHARMCHEM CO.,LTD., we prioritize the purity and quality of Levofloxacin Hemihydrate. Our product is meticulously refined, presenting as a white crystalline powder with a purity exceeding 99%. We adhere to stringent quality control standards, ensuring that each batch meets rigorous pharmaceutical grade specifications. Proper storage is crucial for maintaining the compound's integrity; it should be kept in a cool, dry place, ideally at room temperature between 20°C to 25°C (68°F to 77°F), shielded from direct light and moisture. With a typical shelf life of two years when stored correctly, it offers reliability for long-term pharmaceutical production.

For pharmaceutical manufacturers and formulators, understanding the characteristics of Levofloxacin Hemihydrate is paramount. While it is a highly effective antibiotic, it is a potent API whose use requires careful consideration of its safety profile. Like many powerful medications, it has associated side effects that necessitate professional handling and application. Interactions with certain substances, such as antacids or supplements containing aluminum, magnesium, iron, or zinc, must be managed carefully by taking them at least two hours before or after levofloxacin to ensure optimal absorption. Patients using end-products containing this API should be advised to complete the full prescribed course to prevent antibiotic resistance.

As a leading manufacturer and supplier of pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing Levofloxacin Hemihydrate (CAS 138199-71-0) that meets the highest international quality standards. We offer competitive price options for bulk orders, making us an ideal partner for your pharmaceutical production needs. For those looking to buy or purchase high-quality Levofloxacin Hemihydrate, our team is ready to assist with detailed product specifications, availability, and ordering information. We ensure efficient logistics and dependable delivery to support your continuous supply chain.