Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
NINGBO INNO PHARMCHEM CO.,LTD. is actively investigating the significant potential of Matrine as a novel anti-cancer agent. This natural alkaloid, historically used in traditional Chinese medicine, is now being recognized for its broad-spectrum anti-cancer activities, offering a promising avenue for new therapeutic strategies against various malignancies.
Matrine has demonstrated remarkable efficacy across a range of cancer types, including lung, liver, breast, and leukemia. Its mechanisms of action are diverse, encompassing the inhibition of cancer cell proliferation, induction of cell cycle arrest, promotion of apoptosis, and prevention of metastasis and invasion. This comprehensive action makes Matrine a compelling candidate for drug development, either as a standalone therapeutic or in combination with conventional treatments.
For instance, in lung cancer research, Matrine has shown to inhibit key signaling pathways that drive tumor growth and resistance, such as the PI3K/Akt/mTOR pathway. It also plays a role in overcoming drug resistance, a critical challenge in current cancer therapies. Similarly, in hepatoma research, Matrine has been observed to suppress the stemness of cancer cells and inhibit their proliferation and metastasis, highlighting its potential in treating liver cancer.
The application of Matrine in breast cancer therapy involves inhibiting cell proliferation and migration, promoting apoptosis, and modulating crucial pathways like Wnt/β-Catenin. In leukemia research, Matrine influences cellular metabolism and promotes apoptosis, presenting an option for treating blood cancers. The ability of Matrine to act on multiple fronts against cancer cells positions it as a valuable compound in the fight against this complex disease.
The continuous research into Matrine's synthesis and derivatization, aiming to improve its bioavailability and therapeutic index, further underscores its importance. At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to advancing the study of natural compounds like Matrine, striving to unlock their full potential in revolutionizing cancer treatment and improving patient outcomes.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
