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In the pursuit of efficient and streamlined pharmaceutical manufacturing, direct compression (DC) stands out as a highly desirable method. This process relies on excipients that possess excellent compressibility and flowability. Microcrystalline Cellulose (MCC) is arguably the most prominent direct compression excipient, offering a unique blend of properties that simplify tablet production. NINGBO INNO PHARMCHEM CO.,LTD champions the use of MCC for its critical role in making direct compression a viable and effective manufacturing strategy.
The essence of direct compression lies in its ability to form tablets directly from a powder blend without prior granulation. This requires excipients that can compact under pressure to form robust tablets and flow uniformly into the tablet press dies. MCC’s intrinsic binding properties are key here; its particles deform plastically under pressure, creating extensive inter-particle bonding that results in tablets with high tensile strength. This is a significant advantage, as it allows for the formulation of tablets even with poorly compressible APIs.
Beyond its binding capabilities, MCC’s particle size and morphology contribute to improved powder flow. While some grades might require specific handling, many MCC types offer sufficient flowability for high-speed tableting machines. The microcrystalline cellulose advantages also extend to its inert nature, ensuring compatibility with a wide range of APIs without adverse chemical interactions. This reliability is crucial for maintaining the stability and efficacy of the final drug product.
NINGBO INNO PHARMCHEM CO.,LTD understands that the selection of the appropriate MCC grade is paramount for optimizing direct compression formulations. Different grades exhibit variations in particle size, bulk density, and moisture content, each influencing the tabletability of the blend. Our commitment is to provide pharmaceutical grade MCC that meets stringent quality controls, ensuring consistency and performance. By leveraging the inherent properties of MCC, pharmaceutical manufacturers can reduce processing steps, shorten production cycles, and lower manufacturing costs, all while producing high-quality tablets.
In conclusion, Microcrystalline Cellulose is an indispensable excipient for direct compression tableting. Its exceptional compressibility, coupled with its binding and flow-promoting characteristics, makes it a superior choice for modern pharmaceutical manufacturing. NINGBO INNO PHARMCHEM CO.,LTD is proud to supply high-quality MCC, enabling our clients to harness the full potential of direct compression and deliver effective medications efficiently.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
