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The Mechanism of Action and Broad-Spectrum Efficacy of Florfenicol

Understanding how veterinary medicines work is crucial for effective disease management. Florfenicol, a widely used antibiotic in animal health, boasts a distinct mechanism of action that contributes to its broad-spectrum efficacy. At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing insights into the science behind our products, such as the florfenicol antibiotic mechanism.

Florfenicol belongs to the phenicol class of antibiotics and exerts its effect by inhibiting bacterial protein synthesis. Specifically, it binds reversibly to the 50S subunit of the bacterial 70S ribosome. This binding interferes with the enzymatic activity of peptidyl transferase, the enzyme responsible for forming peptide bonds between amino acids. By blocking this crucial step, florfenicol prevents the elongation of polypeptide chains, effectively halting bacterial growth and replication. The outcome is typically bacteriostatic, meaning it stops bacteria from multiplying, allowing the animal's immune system to clear the infection.

The broad-spectrum efficacy of florfenicol is one of its most significant attributes. It exhibits potent activity against a wide range of Gram-positive bacteria (such as Staphylococcus aureus and Streptococcus spp.) and Gram-negative bacteria (including E. coli, Salmonella spp., Pasteurella spp., and Haemophilus spp.). Furthermore, it is effective against certain Mycoplasma species, which are common causes of respiratory infections in various animals. This wide range of activity makes florfenicol a versatile choice for treating diverse bacterial infections in livestock, poultry, and aquaculture.

Compared to its predecessor, chloramphenicol, florfenicol offers enhanced efficacy and a better safety profile. The fluorine atom in its structure contributes to its increased activity and helps overcome certain resistance mechanisms. Crucially, florfenicol does not carry the same risk of causing irreversible aplastic anemia in humans or animals as chloramphenicol, making it a preferred and safer option in veterinary medicine. The ability to purchase high-quality florfenicol powder from reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that the efficacy of this mechanism is delivered reliably in veterinary formulations.

By understanding the florfenicol antibiotic mechanism, veterinarians and animal producers can better appreciate its value in combating bacterial diseases. NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying this vital antibiotic to support animal health worldwide.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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