In the realm of pharmaceutical synthesis, precision, purity, and reliability are non-negotiable. Manufacturers constantly seek high-quality intermediates that can reliably contribute to the creation of life-saving and health-improving medications. Among these critical building blocks, Menadione Sodium Bisulfite (CAS 130-37-0) holds a significant position, particularly in the development of hematological agents and other specialized therapeutic compounds. As a prominent pharmaceutical chemical manufacturer in China, we are dedicated to supplying this essential intermediate to meet the exacting demands of the global pharmaceutical industry.

Menadione Sodium Bisulfite is a synthetic, water-soluble derivative of menadione, a synthetic form of Vitamin K. While it lacks the direct biological activity of natural Vitamin K (menaquinone and phylloquinone), it serves as a crucial precursor. In vivo, it can be readily converted into active forms of Vitamin K, such as menaquinone-4, which are essential for the post-translational modification of specific proteins. This conversion process underpins its utility in pharmaceutical applications where controlled Vitamin K activity is required.

The primary pharmaceutical application of Menadione Sodium Bisulfite lies in its ability to support the synthesis of blood coagulation factors. These factors, including prothrombin (Factor II), Factor VII, Factor IX, and Factor X, are vitamin K-dependent. By providing a readily available source of Vitamin K activity, menadione sodium bisulfite can be incorporated into therapeutic formulations aimed at managing or preventing bleeding disorders. This makes it an invaluable pharmaceutical intermediate for drug manufacturers focusing on hemostatic agents.

Furthermore, the role of Vitamin K in protein carboxylation extends beyond blood clotting. It is also involved in the synthesis of proteins that regulate calcium binding in bone tissue and vascular walls. This connection opens avenues for its use in pharmaceuticals targeting bone health and cardiovascular conditions. As a high-purity chemical, Menadione Sodium Bisulfite with a purity of over 95% (HPLC) is essential for these sensitive applications, ensuring that the final drug product is safe and effective.

For pharmaceutical companies seeking to purchase Menadione Sodium Bisulfite, sourcing from a reputable manufacturer in China offers distinct advantages. Our facility is equipped with advanced technology and adheres to stringent quality control protocols, guaranteeing lot-to-lot consistency and high purity. We understand the critical nature of pharmaceutical intermediates and are committed to providing a reliable supply chain. We encourage R&D scientists and procurement specialists to inquire about our pricing for bulk purchases of CAS 130-37-0 and to request samples to evaluate our product for their specific synthesis needs.

By partnering with us, pharmaceutical manufacturers can secure a consistent supply of a key intermediate, thereby streamlining their production processes and ensuring the quality of their final pharmaceutical products. We are not just a supplier; we aim to be a trusted partner in your drug development and manufacturing endeavors.