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Menbutone (CAS 3562-99-0): A Vital API for Animal Digestive Health

Menbutone, identified by CAS number 3562-99-0, is a crucial active pharmaceutical ingredient (API) in veterinary medicine. This off-white powder, with the molecular formula C15H14O4 and a molecular weight of 258.27, is widely recognized for its powerful choleretic and cholagogue effects. It plays a significant role in stimulating hepato-digestive activity across a broad spectrum of animal species, making it an indispensable compound for treating various digestive and metabolic disorders.


As a derivative of oxybutyric acid, Menbutone's mechanism of action involves the remarkable stimulation of bile, pancreatic, and gastric juices. Studies have shown that it can increase the secretion of these vital digestive fluids by two to five times their normal levels, with a rapid onset of action typically within one hour, and effects lasting for approximately ten hours. This robust physiological response promotes efficient food transit and assimilation, actively contributing to liver detoxification and restoring the normal function of the stomach, bile, and duodenum. The observed improvements often include a rapid return of appetite, enhanced digestive processes, and improved gastro-enteric movements, directly addressing core issues in affected animals.


The therapeutic versatility of Menbutone is evident in its wide array of applications in veterinary practice. It is indicated for a large number of primary and secondary digestive disorders, either as a sole treatment or as an adjunctive therapy. In cattle, it is used for primary indigestion, such as carbohydrate engorgement or rumen overload, rumen acidosis, and indigestion after consuming moldy feed, as well as food poisoning, hepatic and pancreatic insufficiency, bloat, impaction, constipation, and loss of appetite. For sheep and goats, similar indications apply, along with its use in cases of pregnancy toxemia. In canines, Menbutone addresses constipation, anorexia, intestinal atony, pancreatic insufficiency, and nutritional imbalances, providing a stimulatory effect on hepatic and bile secretion. Administered parenterally, typically via intramuscular or intravenous injection, Menbutone is a vital tool for veterinarians globally.


Regarding its safety profile, Menbutone is generally considered to have a relatively wide safety margin, with the European Commission establishing that no maximum residue limit (MRL) is required for this drug due to its rapid elimination from the body. However, precautions are essential. Accidental high doses can lead to acute toxicity, with cardiac muscle, liver, and kidneys being the main target organs. Therefore, it is not recommended for animals suffering from existing cardiac or hepatic disorders, especially in overdosing situations. Intravenous administration should always be performed slowly, and its use during the last third of pregnancy in cattle is also cautioned against. Adherence to recommended dosages and veterinarian prescription is crucial for safe and effective treatment.


The efficacy and safety of Menbutone are profoundly dependent on its quality and purity. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-grade Menbutone, ensuring that every batch undergoes stringent quality control processes. Our commitment extends to robust analytical validation, employing advanced methods such as High-Performance Liquid Chromatography (HPLC) to guarantee the purity and consistency of our product. This meticulous approach ensures that our Menbutone meets the exacting standards required for pharmaceutical applications, aligning with international guidelines for bioanalytical method validation.


As a leading Menbutone manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is your trusted partner for premium active pharmaceutical ingredients. We understand the critical importance of reliable sourcing for veterinary pharmaceuticals. For those interested to buy Menbutone in bulk or inquire about the competitive price, our dedicated team is prepared to offer comprehensive support and facilitate a streamlined purchase process. We are committed to fostering long-term partnerships by delivering consistent quality and exceptional service, solidifying our position as a preferred manufacturer and supplier for the global veterinary health industry.

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