Methyl 2,3-dichloropropionate (CAS 3674-09-7) is a chemical compound that plays a significant role in the landscape of organic synthesis and the pharmaceutical industry. As a key intermediate, its availability in high purity and at competitive prices is crucial for researchers and manufacturers alike. This article delves into the properties, synthesis routes, diverse applications, and the global supply chain for this important chemical.

Chemical Profile and Properties

Methyl 2,3-dichloropropionate, identified by CAS number 3674-09-7, is an ester of 2,3-dichloropropionic acid. It presents as a clear, colorless to slightly yellow liquid, with physical characteristics such as a density of 1.325 g/mL at 25°C and a boiling point of 63°C at 13 hPa. Its flash point is 63°C. These properties make it a manageable reagent for various chemical processes. The typical purity offered by manufacturers is 97% minimum, ensuring its efficacy in sensitive synthetic applications.

Synthesis of Methyl 2,3-dichloropropionate

The synthesis of Methyl 2,3-dichloropropionate often involves the chlorination of methyl acrylate. A common method described in literature involves passing chlorine gas into methyl acrylate in the presence of a catalyst or solvent like dimethylformamide (DMF). The reaction requires careful temperature control, typically below 40°C, and the product is isolated through vacuum distillation. For instance, reacting methyl acrylate with chlorine gas under controlled conditions yields Methyl 2,3-dichloropropionate with good yields, often around 77.2% with a purity of 98%. Understanding these synthesis pathways helps in appreciating the manufacturing process and quality control involved when you buy Methyl 2,3-dichloropropionate.

Applications in Industry

The primary application of Methyl 2,3-dichloropropionate is as a vital pharmaceutical intermediate. It serves as a building block in the synthesis of complex molecules, including certain APIs. Beyond pharmaceuticals, it finds use in general organic chemistry as a reagent for various synthetic transformations. For example, it can be used to prepare 2-chloro-acrylic acid methyl ester through heating or in the preparation of specific analogs in medicinal chemistry research. Professionals looking to secure a consistent supply for these applications can purchase Methyl 2,3-dichloropropionate from specialized chemical suppliers.

Finding Global Suppliers

The global market for Methyl 2,3-dichloropropionate is served by numerous suppliers, with a significant concentration of manufacturers in China. When searching for a reliable Methyl 2,3-dichloropropionate supplier, it’s essential to vet potential partners based on their product specifications, quality certifications, and customer service. Companies that provide detailed product information, including CAS number, molecular formula, and safety data sheets (SDS), are preferred. We recommend comparing the CAS 3674-09-7 price and lead times from various manufacturers to ensure you are obtaining the best value for your investment. NINGBO INNO PHARMCHEM CO.,LTD. stands as a dedicated provider of such essential intermediates, committed to facilitating efficient procurement for clients worldwide.

In summary, Methyl 2,3-dichloropropionate is a critical intermediate with well-defined properties and applications. Whether for pharmaceutical research or industrial synthesis, sourcing from a reputable manufacturer offering high purity and competitive pricing is key. Exploring the synthesis and application of this compound can further inform your purchasing decisions and strengthen your supply chain.