Methyl(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserinate, identified by its CAS number 124605-42-1, stands as a pivotal chemical compound in the intricate world of pharmaceutical synthesis. This high-purity substance serves as a critical intermediate, forming the backbone for the production of highly effective therapeutic agents. As a specialized chemical, its precise molecular structure and stereochemistry are paramount, ensuring the efficacy and safety of the final drug products it contributes to.

Known by various synonyms such as N-tert-butoxycarbonylphenylisoserine methyl ester and Methyl (2R,3S)-N-Benzoyl-3-Phenylisoserine, this compound possesses a molecular formula of C17H17NO4 and a molecular weight of 299.321. It typically presents as an off-white crystalline powder, a characteristic indicator of its purified state. The consistent high assay of this material, typically exceeding 98.0%, reflects the rigorous quality control standards maintained during its production. Such high purity is indispensable for its downstream applications, where even minor impurities can compromise the integrity of the final pharmaceutical active ingredients.

The physical and chemical properties of Methyl(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserinate are well-defined, contributing to its stability and predictable behavior in chemical reactions. It has a melting point of 132-133ºC and a boiling point of approximately 540.3±50.0 °C at 760 mmHg. Its density is measured at 1.2±0.1 g/cm3, and the flash point is 280.6±30.1 °C. These parameters are crucial for safe handling, transportation, and storage, ensuring the product retains its quality over time. A low vapor pressure of 0.0±1.5 mmHg at 25°C further attests to its stability under standard conditions.

The primary application of Methyl(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserinate lies in its role as an essential intermediate for the synthesis of vital anticancer drugs. Specifically, it is a key precursor for Cabazitaxel (CAS: 183133-96-2) and Paclitaxel (CAS: 33069-62-4). Both Cabazitaxel and Paclitaxel are members of the taxane family, renowned for their efficacy in treating various cancers. The availability of a high-quality intermediate like Methyl(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserinate is therefore fundamental for pharmaceutical companies engaged in the large-scale manufacturing of these life-saving oncology medications. Its specific stereochemistry (2R,3S) is critical for conferring the desired biological activity in the final drug molecules, highlighting the importance of precise synthesis pathways.

At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing Methyl(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserinate that meets the most stringent pharmaceutical requirements. Our product is meticulously prepared and tested to ensure its exceptional purity and consistent quality, making it a reliable choice for your synthesis needs. We understand the critical nature of pharmaceutical intermediates and adhere to robust manufacturing processes to deliver a product that exceeds industry standards. For optimal preservation of its properties, the product should be stored in a cool, ventilated place, and is typically supplied in 25 kg drums, with custom packaging options available to suit specific customer requirements.

As a leading manufacturer and trusted supplier of advanced pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is well-positioned to meet the global demand for Methyl(2R,3S)-N-tert-butoxycarbonyl-3-phenylisoserinate. We offer competitive prices and a seamless procurement process for those looking to buy or purchase this essential compound. Our commitment to excellence extends from product quality to reliable supply chain management, ensuring that our partners receive their orders efficiently and consistently. For more information regarding availability, specifications, or to request a quotation, please reach out to us. We look forward to supporting your pharmaceutical development and manufacturing endeavors with our premium chemical solutions.