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Methyl 3-Bromo-2-fluorobenzoate: A Key Intermediate for Organic Synthesis

Methyl 3-Bromo-2-fluorobenzoate, identified by its CAS number 206551-41-9, stands as a crucial chemical intermediate in the realm of organic synthesis. This compound, also known by synonyms such as methyl 2-fluoro-3-bromobenzoate or Benzoic acid, 3-bromo-2-fluoro-, methyl ester, is highly valued for its unique chemical structure, which enables its versatile application in creating more complex organic molecules. Its precise molecular configuration makes it an indispensable building block for various advanced chemical processes, particularly in the pharmaceutical and agrochemical industries.


The chemical profile of Methyl 3-Bromo-2-fluorobenzoate is well-defined by its molecular formula C8H6BrFO2 and a molecular weight of approximately 233.03400. Physically, it typically presents as a white to pale yellow solid or off-white powder, sometimes described as a crystalline powder. Key physical and chemical properties include a density of 1.578 g/cm³, a boiling point of around 255.391°C, and a flash point of 108.257°C. The compound exhibits a refractive index of 1.531 and a melting point in the range of 35-37°C, further confirming its distinct characteristics. It is notably soluble in Methanol, facilitating its use in various solvent-based reactions.


Its primary application lies in its role as an intermediate for organic synthesis. Methyl 3-Bromo-2-fluorobenzoate serves as a versatile precursor for the creation of new chemical entities, acting as a critical component in multi-step synthesis pathways. The presence of bromine and fluorine atoms on the benzene ring, coupled with the methyl ester group, provides diverse reaction sites, making it highly reactive and adaptable. This makes it an invaluable asset for chemists developing novel compounds with specific functionalities, contributing significantly to advancements in medicinal chemistry, material science, and other specialized chemical fields. Its high purity and consistent quality are paramount to ensuring the efficiency and success of these complex synthetic routes.


At NINGBO INNO PHARMCHEM CO.,LTD., we understand the critical importance of purity and consistency in chemical intermediates. Our Methyl 3-Bromo-2-fluorobenzoate consistently meets rigorous quality standards, boasting a purity of ≥99.0% as verified by HPLC. This commitment to superior quality ensures that our product performs reliably in demanding synthetic applications, minimizing impurities and maximizing reaction yields for our customers. Each batch undergoes stringent quality control checks to guarantee its adherence to specified parameters, providing peace of mind to researchers and manufacturers alike.


Proper storage and handling are essential to maintain the integrity of Methyl 3-Bromo-2-fluorobenzoate. It should be stored in a cool, ventilated place, ideally sealed dry at room temperature, to prevent degradation and ensure its long-term stability. While generally stable, standard safety precautions for handling chemical reagents should be observed, as it may be a potential irritant. For packaging, Methyl 3-Bromo-2-fluorobenzoate is typically supplied in 25 kg drums, though NINGBO INNO PHARMCHEM CO.,LTD. offers flexible packaging options tailored to meet specific customer requirements, ensuring convenient and safe delivery.


As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality Methyl 3-Bromo-2-fluorobenzoate to a global clientele. We offer competitive price options for bulk orders and ensure efficient global distribution. For those looking to buy or purchase this essential organic synthesis intermediate, our expert team is ready to assist with inquiries, technical support, and seamless order fulfillment. We pride ourselves on being a reliable partner, committed to supplying premium chemical products that fuel innovation and progress in diverse industries worldwide. Contact us to learn more about our product offerings and how we can meet your specific chemical sourcing needs.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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