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Direct compression tableting offers significant advantages in pharmaceutical manufacturing, including reduced processing time, fewer manufacturing steps, and lower costs. The success of this technique hinges on the properties of the excipients used, and Microcrystalline Cellulose (MCC) stands out as the premier choice. NINGBO INNO PHARMCHEM CO.,LTD. explores why MCC is so integral to efficient direct compression.
The inherent characteristics of MCC, such as its excellent flowability and compressibility, are what make it ideal for direct compression. Unlike materials that require granulation to achieve adequate compaction, MCC can be directly compressed into tablets with high hardness and low friability. This ability is rooted in the microcrystalline cellulose manufacturing process, which yields particles that readily deform plastically under pressure, creating strong interparticle bonds. The ease with which manufacturers can buy microcrystalline cellulose powder for these applications is a testament to its widespread adoption.
As a binder, MCC ensures tablet cohesion, while its capacity to improve powder flow aids in consistent die filling. This combination is crucial for achieving uniform tablet weights and drug content, which are critical quality attributes in pharmaceutical products. The efficacy of microcrystalline cellulose binder properties in direct compression is well-established, providing a reliable foundation for tablet manufacturing. Furthermore, MCC’s role as a disintegrant ensures that these robust tablets can still break down effectively in the body to release the API.
The importance of microcrystalline cellulose as a pharmaceutical excipient cannot be overstated in the context of direct compression. It allows formulators to bypass granulation, significantly simplifying the manufacturing workflow. This efficiency is often a primary driver for companies choosing microcrystalline cellulose direct compression methods. Adhering to strict microcrystalline cellulose quality control is paramount to ensure that the material consistently delivers these benefits, batch after batch.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to supplying high-quality MCC that empowers pharmaceutical manufacturers to leverage the full benefits of direct compression. By choosing the right excipients, companies can achieve greater efficiency, reduce production costs, and deliver superior pharmaceutical products to the market.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
