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Mildronate and Cardiovascular Health: A Comprehensive Look at its Protective Role

Mildronate, known by its CAS number 76144-81-5, has emerged as a significant compound in the field of cardiovascular medicine. Its primary function is to enhance the heart's ability to function efficiently, especially when it faces challenges like reduced oxygen supply (ischemia). This makes it a crucial component in the management of various heart-related ailments. NINGBO INNO PHARMCHEM CO., LTD recognizes the importance of such compounds in advancing healthcare solutions.

The cardioprotective effects of Mildronate stem from its unique mechanism of action, which involves modulating cellular energy metabolism. By inhibiting the carnitine-dependent pathway for fatty acid oxidation, Mildronate encourages the heart muscle to utilize glucose for energy production. This shift is particularly beneficial during ischemic events, as glucose metabolism requires less oxygen than fatty acid oxidation. This process helps preserve myocardial function and prevents the accumulation of toxic byproducts that can damage heart cells. The ability of Mildronate to inhibit carnitine biosynthesis is central to its efficacy in these conditions.

Clinical applications for Mildronate are widespread, particularly in Eastern European countries where it is a commonly prescribed medication. It is used to treat a range of cardiovascular conditions, including stable angina, chronic heart failure, and cardiomyopathy. By improving the heart's energy supply and protecting it from damage, Mildronate helps alleviate symptoms and improve the overall quality of life for patients. The effectiveness of Mildronate in stable angina cases is well-documented.

Furthermore, Mildronate's role extends to improving recovery after acute ischemic attacks. Its beneficial effects on tissue energy reserves and its cytoprotective properties contribute to faster and more effective healing. The pharmaceutical industry's demand for reliable sources of compounds like Mildronate is high, and NINGBO INNO PHARMCHEM CO., LTD is dedicated to meeting this need with purity and consistency. Understanding the intricacies of how to inhibit carnitine biosynthesis allows for targeted therapeutic interventions in cardiology.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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