Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
At NINGBO INNO PHARMCHEM CO.,LTD., we focus on the fundamental science behind the chemicals we supply. Probenecid Sodium Salt (CAS 23795-03-1) is a prime example of a compound whose molecular mechanisms translate into significant therapeutic benefits, particularly in managing gout and enhancing antibiotic treatments.
The primary molecular action of Probenecid Sodium Salt revolves around its interaction with organic anion transporters (OATs), a family of proteins embedded in cell membranes that are critical for the transport of various anionic substances. In the kidneys, OATs are responsible for reabsorbing uric acid from the glomerular filtrate back into the bloodstream. By competitively binding to these OATs, Probenecid Sodium Salt effectively inhibits this reabsorption process. This leads to a marked increase in the urinary excretion of uric acid, thereby lowering serum uric acid levels and providing relief for individuals suffering from gout. The principle of probenecid to inhibit uric acid excretion is a cornerstone of its application in treating hyperuricemia.
Furthermore, these same OATs are involved in the elimination of certain antibiotics from the body. When Probenecid Sodium Salt is co-administered with these antibiotics, it impedes their renal clearance. This inhibition results in higher plasma concentrations of the antibiotics and extends their half-life, making the treatment more effective and potentially reducing the required dosage or frequency. Understanding how to leverage this property by learning about probenecid buy options is crucial for pharmaceutical developers.
The utility of Probenecid Sodium Salt extends to its physical properties, specifically its water solubility. The sodium salt form dissolves easily in aqueous solutions, a significant advantage over the less soluble free acid form of probenecid. This enhanced solubility makes it an ideal choice for laboratory applications, including the preparation of solutions for cell-based assays. The use of water soluble probenecid for assays ensures greater convenience and consistency in experimental outcomes.
NINGBO INNO PHARMCHEM CO.,LTD. is a reliable source for high-purity Probenecid Sodium Salt. We understand the stringent quality requirements for pharmaceutical intermediates and are dedicated to meeting these standards. For researchers and manufacturers seeking to explore the therapeutic potential of Probenecid Sodium Salt, our commitment to quality and supply chain integrity makes us an ideal partner.
In essence, Probenecid Sodium Salt's molecular design allows it to play a pivotal role in both metabolic disease management and the optimization of antimicrobial therapies. Its ability to modulate transporter activity at a molecular level underscores its importance in the pharmaceutical industry. NINGBO INNO PHARMCHEM CO.,LTD. is proud to supply this vital compound to support ongoing advancements in healthcare.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
