In the intricate world of pharmaceutical synthesis, specific chemical intermediates act as linchpins, enabling the creation of vital medications. One such crucial compound is N-(2'-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride (CAS: 482577-59-3). As a leading manufacturer and supplier of this high-purity intermediate from China, we aim to provide a comprehensive overview for R&D scientists, formulators, and procurement specialists.

Product Profile: N-(2'-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride

This compound is fundamentally an advanced organic molecule that serves as a precursor in the synthesis of Angiotensin II Receptor Blockers (ARBs), most notably Valsartan. Its chemical name itself provides clues to its structure: a biphenyl core substituted with a cyano group and a methyl ester of L-valine, complexed as a hydrochloride salt.

Key specifications that underscore its value include:

• Appearance: Typically a white crystalline powder, indicating a well-defined solid structure.
• Purity: A minimum assay of ≥98.5% (HPLC) ensures that the material is of high quality, suitable for demanding pharmaceutical applications.
• Controlled Impurities: Critical for pharmaceutical intermediates, the levels of related substances like 2-Cyano-4'-bromomethylbiphenyl (≤0.5%) and other unknown impurities (≤1.0%) are strictly managed.
• Loss on Drying: A maximum of ≤1.0% indicates low moisture content, contributing to stability and accurate handling.
• Molecular Formula & Weight: C20H23ClN2O2 and 358.862 g/mol, providing essential chemical identification.

Applications and Significance in Pharmaceutical Synthesis

The primary application for N-(2'-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride is its role as an intermediate in the synthesis of Valsartan. Valsartan is a critical drug used to treat high blood pressure, heart failure, and to improve survival after a heart attack. The quality of this intermediate directly impacts the quality and efficacy of the final drug product. For pharmaceutical companies looking to buy this compound, ensuring it meets rigorous industry standards is paramount.

Why Source from a Reputable Manufacturer in China?

As a direct manufacturer in China, we offer significant advantages:

• Quality Assurance: Our vertically integrated production process allows for stringent quality control at every stage.
• Competitive Pricing: We provide cost-effective solutions, especially for bulk quantities, enabling better budget management for your projects. Requesting a quote from us is the first step to realizing cost savings.
• Reliable Supply: We maintain robust inventory and production capabilities to ensure a consistent and timely supply for our clients worldwide.
• Technical Expertise: Our team possesses deep knowledge of organic synthesis and can provide support regarding product specifications and applications.

Storage and Handling Recommendations

To maintain the integrity of the product, it is recommended to store N-(2'-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride in a cool, ventilated place. Proper packaging, such as 25 kg drums, is utilized to protect the material during transit and storage.

Partnering for Pharmaceutical Success

When you choose to purchase N-(2'-Cyanobiphenyl-4-ylmethyl)-L-valine Methyl Ester Hydrochloride from us, you are selecting a partner committed to excellence. We understand the critical nature of pharmaceutical intermediates and strive to be your reliable source for high-quality chemicals. Contact us today to discuss your bulk requirements and receive a competitive quote.