In the realm of fine chemicals and pharmaceutical manufacturing, certain molecules stand out for their versatility and indispensable roles. N-(2-Hydroxyethyl)piperazine, identified by CAS number 103-76-4, is precisely one such compound. This hydroxyalkyl-substituted piperazine derivative serves as a fundamental building block, enabling the creation of complex molecules critical for both therapeutic applications and advanced industrial processes. For scientists and formulators, understanding its capabilities and secure sourcing is key.

The Chemical Profile of N-(2-Hydroxyethyl)piperazine

N-(2-Hydroxyethyl)piperazine is characterized by its dual functionality: the piperazine ring offers reactive nitrogen atoms, while the hydroxyethyl group provides a hydroxyl functionality. This combination makes it an excellent intermediate for a wide range of organic synthesis reactions. Typically supplied as a colorless to light yellow liquid, its high purity, often exceeding 99.5%, is essential for demanding applications where even minor impurities can impact reaction yields or final product performance. Key physical properties, such as its boiling point of approximately 245°C, are important considerations for process design.

Applications Driving Innovation

The significance of N-(2-Hydroxyethyl)piperazine is evident in its diverse application spectrum:

• Pharmaceutical Synthesis: It is a cornerstone intermediate for numerous Active Pharmaceutical Ingredients (APIs). Its structure is integral to the development of various therapeutic agents, including certain neuroleptic drugs. Researchers often seek to buy this compound for drug discovery and development pipelines.
• Surfactants: The molecule’s structure allows for its incorporation into surfactant molecules, which are vital in detergents, emulsifiers, and wetting agents across many industries.
• Polyurethane Catalysts: It plays a role in synthesizing catalysts used in polyurethane production, influencing the curing process and final material properties of foams, coatings, and elastomers.
• Corrosion Inhibitors: Its ability to complex with metal ions makes it valuable in formulating effective corrosion inhibitors.
• Electronic Chemicals: N-(2-Hydroxyethyl)piperazine also finds application in the specialized field of electronic chemicals.

Securing Your Supply Chain: Purchasing N-(2-Hydroxyethyl)piperazine

For businesses looking to purchase N-(2-Hydroxyethyl)piperazine, sourcing from a reliable manufacturer is critical. When inquiring about availability and price, it's beneficial to look for suppliers who can offer:

• High-Purity Grades: Ensuring the ≥99.5% assay is crucial for sensitive applications.
• Bulk Packaging: Availability in standard industrial packaging like 200 kg drums facilitates large-scale operations.
• Competitive Pricing: Direct inquiries to manufacturers, especially those based in China, can provide significant cost advantages.
• Technical Documentation: Access to Certificates of Analysis (CoA) and Safety Data Sheets (SDS) is essential for quality and safety compliance.

By prioritizing these aspects, research scientists and procurement specialists can confidently source N-(2-Hydroxyethyl)piperazine, a truly indispensable intermediate for modern chemical and pharmaceutical innovation. Engage with reputable suppliers to obtain quotes and samples to verify quality for your specific synthesis needs.