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N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester: A Key Chemical Intermediate for Synthesis

In the vast landscape of chemical synthesis, certain intermediates play a disproportionately significant role due to their versatility and the precise functionalities they offer. N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester, identified by its CAS number 117833-18-8, is one such compound. Valued for its role as a synthesis material intermediate, it is a compound that many R&D scientists and procurement managers need to source efficiently.

Chemical Profile and Properties

N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester possesses the molecular formula C10H17NO5 and a molecular weight of approximately 231.25 g/mol. It is typically presented as a white solid, a characteristic that aids in its handling and identification. Its key feature is the presence of the N-acetyl group and a tert-butyl ester on one of the carboxyl groups of aspartic acid. This protection strategy is fundamental in synthetic organic chemistry, allowing for selective modification and coupling reactions.

Applications in Organic Synthesis

The primary application of CAS 117833-18-8 is as a building block in the synthesis of more complex organic molecules. Its structure makes it particularly useful in:

  • Peptide Synthesis: As a protected amino acid derivative, it is instrumental in constructing peptide chains for research, therapeutics, and diagnostics. The tert-butyl ester provides acid-labile protection for the beta-carboxyl group.
  • Pharmaceutical Intermediates: It serves as a precursor or intermediate in the multi-step synthesis of various pharmaceutical compounds and APIs.
  • Fine Chemical Manufacturing: Its controlled reactivity profile makes it a valuable component in the production of specialized fine chemicals.

The high purity, often specified as 99% minimum assay, is critical for ensuring successful outcomes in these applications, preventing unwanted side reactions and simplifying purification processes.

Sourcing and Availability

For professionals looking to buy N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester, identifying reliable manufacturers and suppliers is key. Companies that specialize in providing high-quality synthesis intermediates, often based in regions like China, are primary sources. When inquiring, it's important to ask about pricing, minimum order quantities (e.g., 25kg drums), and delivery timelines. A responsive supplier will provide detailed product information and technical support.

Conclusion

N-Acetyl-L-Aspartic Acid Beta-tert-butyl Ester (CAS 117833-18-8) is a cornerstone intermediate for many advanced chemical synthesis projects. Its well-defined properties and crucial role in constructing complex molecules underscore its importance. For procurement, focusing on high purity and partnering with experienced manufacturers and suppliers ensures successful sourcing and project execution. If you need to purchase this vital intermediate, explore options from reputable suppliers to secure quality and competitive pricing.

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