NINGBO INNO PHARMCHEM CO.,LTD. is proud to present N-Boc-L-Tert-Leucine (CAS 62965-35-9), a premium chemical raw material indispensable in modern pharmaceutical research and development. This protected amino acid is a cornerstone building block, particularly valued for its unique properties in complex organic synthesis and peptide chemistry.
With the chemical name N-Boc-L-tert-Leucine, and also known by synonyms such as Boc-L-tert-Leu-OH or (S)-2-(tert-Butoxycarbonylamino)-3,3-dimethylbutanoic acid, this compound boasts a molecular formula of C11H21NO4 and a molecular weight of 231.29 g/mol. It typically appears as a white crystalline powder, signaling its high degree of purity and solid form suitable for various laboratory and industrial applications.
The exceptional quality of our N-Boc-L-Tert-Leucine is confirmed by rigorous testing, demonstrating a purity of ≥ 98% via HPLC and an optical purity of ≥ 99% ee (L-enantiomer). Its melting point ranges from 85-90°C, providing a reliable physical characteristic. Solubility is noted as soluble in DMF and DMSO, with slight solubility in water, making it adaptable to different reaction environments. Recommended storage conditions are 2-8°C under a dry, inert atmosphere to maintain its stability and integrity over time.
The significance of N-Boc-L-Tert-Leucine lies in its dual protective and structural roles. The Boc (tert-butoxycarbonyl) group serves as a highly effective temporary protecting group for the amine function, crucial in step-wise synthesis, especially in solid-phase peptide synthesis (SPPS). The tert-butyl group within the leucine side chain introduces considerable steric hindrance. This characteristic is invaluable for designing constrained peptides and peptidomimetics, molecules designed to mimic natural peptides but with enhanced stability, bioavailability, or altered pharmacological profiles. Such structures are frequently explored in drug discovery efforts.
As a chiral building block, N-Boc-L-Tert-Leucine is also vital in asymmetric synthesis, enabling the creation of stereochemically defined complex molecules. This is critically important in medicinal chemistry, where the biological activity of a drug often depends on its specific enantiomeric form.
Applications span a wide range within the pharmaceutical industry, including the development of therapeutics for serious conditions. Its use in designing and synthesizing peptides and small molecules contributes significantly to research areas such as anticancer and antiviral drug development. The demand for high-purity protected amino acids like N-Boc-L-Tert-Leucine is continuously growing as peptide-based drugs and chiral pharmaceuticals gain prominence.
Ensuring the quality and consistency of raw materials is paramount in pharmaceutical manufacturing and research. NINGBO INNO PHARMCHEM CO.,LTD. adheres to stringent quality control measures throughout the production process. Each batch of N-Boc-L-Tert-Leucine is thoroughly tested to meet the specified purity and optical purity standards before being dispatched. A Certificate of Analysis (COA) is provided with every shipment, offering customers transparency and assurance of the product's quality and compliance with specifications.
Packaging options are designed for convenience and safety, typically including various drum sizes or other suitable containers to protect the material during transport and storage. Minimum order quantities are set to accommodate both research-scale and larger production needs, providing flexibility for diverse customer requirements.
For researchers and manufacturers looking to procure this essential raw material, NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable source. As a dedicated manufacturer and supplier of fine chemicals and pharmaceutical intermediates, we understand the critical need for timely delivery and competitive pricing.
Information regarding the current price, available quantities, and detailed specifications can be obtained by contacting our sales team directly. We strive to offer a transparent and competitive price structure based on order volume and specific requirements. Our streamlined process makes it straightforward for customers worldwide to buy or purchase N-Boc-L-Tert-Leucine.
Whether you require a sample for R&D purposes or are planning a bulk purchase, NINGBO INNO PHARMCHEM CO.,LTD. is equipped to handle your needs efficiently. Sample requests, payment terms (such as TT and LC are standard options, with others negotiable), and estimated delivery timelines are managed professionally to ensure a smooth transaction from inquiry to delivery.
Choosing N-Boc-L-Tert-Leucine from NINGBO INNO PHARMCHEM CO.,LTD. means partnering with a supplier committed to quality, consistency, and customer satisfaction. We are dedicated to supporting advancements in pharmaceutical science by providing high-grade chemical building blocks essential for innovation. Learn more about how to buy this key protected amino acid and discuss your specific requirements with our expert team today.
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to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.