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N-Carbobenzyloxy-L-aspartic Acid: A Vital Component in Pharmaceutical Synthesis

The pharmaceutical industry relies heavily on a diverse array of chemical intermediates to synthesize life-saving drugs and therapies. N-Carbobenzyloxy-L-aspartic acid (CAS 1152-61-0) is a particularly important compound, serving as a fundamental building block in the development of various pharmaceuticals. NINGBO INNO PHARMCHEM CO.,LTD. is a leading manufacturer and supplier of this critical intermediate from China.

N-Carbobenzyloxy-L-aspartic acid, often abbreviated as Z-Asp-OH or Cbz-Asp-OH, is derived from the amino acid L-aspartic acid. The carbobenzyloxy (Cbz) group acts as a protective cover for the alpha-amino group, preventing unintended reactions during complex synthetic pathways. This protection is essential in multistep organic synthesis, especially in the creation of peptides and peptidomimetics which are integral to many modern pharmaceuticals. The compound is typically a white crystalline powder, meeting high purity standards (e.g., USP, BP, FCC) vital for pharmaceutical applications.

The synthesis of N-Carbobenzyloxy-L-aspartic acid involves the reaction of L-aspartic acid with Benzyl chloroformate. This process, carefully managed by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD., ensures the production of a high-quality intermediate with a consistent molecular formula (C12H13NO6) and molecular weight (267.23 g/mol). The strategic protection offered by the Cbz group allows for controlled coupling reactions, a prerequisite for building intricate pharmaceutical structures.

The primary application of N-Carbobenzyloxy-L-aspartic acid in the pharmaceutical sector is its use in synthesizing peptide-based drugs. Many therapeutic peptides require precise amino acid sequences, and Z-Asp-OH provides a stable and reactive component for their construction. It also serves as a chiral building block in the synthesis of non-peptide small molecules that form the basis of numerous drug candidates. The ability to buy N-Carbobenzyloxy-L-aspartic acid from reliable manufacturers in China, such as NINGBO INNO PHARMCHEM CO.,LTD., ensures that pharmaceutical companies can maintain their production pipelines.

As a significant player in the chemical manufacturing landscape, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing pharmaceutical researchers and manufacturers with dependable access to N-Carbobenzyloxy-L-aspartic acid. Our dedication to quality and our competitive pricing make us an ideal partner for your pharmaceutical synthesis needs. We invite you to contact us to learn more about how our N-Carbobenzyloxy-L-aspartic acid can support your drug development and manufacturing processes.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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