N-Fmoc-N-methyl-D-alanine: A Pivotal Compound in Advanced Chemical Synthesis

N-Fmoc-N-methyl-D-alanine, identified by its CAS No: 138774-92-2, stands as a highly significant amino acid derivative within the realm of organic chemistry and pharmaceutical development. This sophisticated compound, also recognized by its various aliases such as Fmoc-D-Me-Ala-OH, (2R)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]propanoic acid, and N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-D-alanine, plays a crucial role in a multitude of research and industrial applications, particularly as a vital building block in peptide synthesis and as a pharmaceutical intermediate.

At NINGBO INNO PHARMCHEM CO.,LTD., we specialize in the meticulous synthesis and supply of high-purity chemical compounds, including N-Fmoc-N-methyl-D-alanine. Our commitment to quality ensures that this product meets stringent specifications, appearing as a white powder with an impressive assay of u226598.0%. This high purity is paramount for its effective use in sensitive chemical reactions and pharmaceutical applications, where even minor impurities can compromise end-product integrity and performance.

The chemical profile of N-Fmoc-N-methyl-D-alanine is well-defined, providing a clear understanding of its behavior and optimal handling conditions. Its molecular formula is C19H19NO4, with a molecular weight of 325.358. Key physical properties include a density of 1.3u00b10.1 g/cm3, a boiling point of 514.9u00b129.0 u00b0C at 760 mmHg, and a flash point of 265.2u00b124.3 u00b0C. The exact mass is 325.131409, with a PSA of 66.84000 and LogP of 4.03. These characteristics underscore its stability and reactivity, making it a reliable component for diverse synthetic pathways.

The primary application of N-Fmoc-N-methyl-D-alanine lies in its utility as a versatile amino acid derivative and a crucial pharmaceutical intermediate. In pharmaceutical research and development, it serves as a chiral building block, enabling the synthesis of complex molecules with specific stereochemistry, which is often vital for drug efficacy and safety. Its Fmoc (9-fluorenylmethoxycarbonyl) protective group allows for controlled and selective reactions, indispensable in multi-step organic synthesis, particularly in peptide chemistry where precise control over amino acid coupling is required.

Proper storage and handling are essential to maintain the quality and integrity of N-Fmoc-N-methyl-D-alanine. The compound should be stored in a cool place, ideally between 2-8u00b0C, with its container tightly closed in a dry and well-ventilated area. When preparing stock solutions, it's generally advisable to use an appropriate solvent and store solutions in separate packages to prevent degradation from repeated freezing and thawing cycles. For long-term preservation of stock solutions, storing at -80u00b0C for up to 6 months or at -20u00b0C for up to 1 month is recommended. Increasing solubility can often be aided by gently heating the tube to 37u00b0C and applying ultrasonic oscillation. This product is intended strictly for research use only and is not for human or therapeutic applications.

As a leading manufacturer and supplier of specialty chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality N-Fmoc-N-methyl-D-alanine for your research and production needs. We offer flexible packaging options, typically in 25kg drums, with customization available to meet specific customer requirements. For those looking to purchase this essential compound, we ensure competitive price points coupled with reliable global shipping. We encourage prospective buyers to buy directly from a trusted and experienced source like NINGBO INNO PHARMCHEM CO.,LTD. to guarantee product authenticity and purity, ensuring your projects proceed with the highest quality materials.