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N,N'-Dimethyl-1,3-Propanediamine (CAS 111-33-1): Key Chemical Intermediate

N,N'-Dimethyl-1,3-propanediamine (CAS 111-33-1) stands as a pivotal chemical compound in various industrial sectors. This versatile diamine, also known by synonyms such as N1,N3-dimethylpropane-1,3-diamine, is a clear, colorless liquid distinguished by its unique chemical structure and reactive properties. Its significance is underscored by its wide array of applications as a crucial intermediate in organic synthesis.


Chemically, N,N'-Dimethyl-1,3-propanediamine has the molecular formula C5H14N2 and a molecular weight of approximately 102.18 g/mol. Its physical characteristics make it easy to handle in industrial settings; it is a clear, colorless liquid with a distinct ammonia-like odor. Key physical properties include a boiling point around 145°C, a melting point of approximately -78.72°C, and a density of 0.817 g/mL at 25°C. The flash point is notably low, around 20°C, indicating its flammable nature and the need for careful handling and storage under appropriate conditions. A highly desirable property for many chemical processes is its complete miscibility with water, allowing for versatile formulation and reaction conditions.


The applications of N,N'-Dimethyl-1,3-propanediamine are extensive and critical to several industries. It serves as an indispensable pharmaceutical intermediate, playing a vital role in the synthesis of various active pharmaceutical ingredients (APIs). Its diamine structure provides reactive sites that are essential for building complex molecular frameworks required in drug development. Beyond pharmaceuticals, it is widely utilized in the production of agrochemicals, contributing to the synthesis of compounds that enhance crop protection and yield. Its reactivity makes it an excellent building block for creating new and effective agricultural chemicals.


Furthermore, this compound finds significant use in the dyestuffs industry. The presence of amine groups allows for its incorporation into dye molecules, influencing color, stability, and affinity for various fibers. It is also a fundamental component in general organic synthesis, where it can be employed in reactions such as aminations, cross-linking, and as a raw material for specialty chemicals. Its ability to act as a precursor for various derivatives makes it a valuable asset for chemists developing novel compounds across diverse applications.


Given its chemical nature, N,N'-Dimethyl-1,3-propanediamine requires careful handling. It is classified as a highly flammable liquid and vapor, and can cause severe skin burns and eye damage. Proper personal protective equipment, including eye protection and gloves, along with adequate ventilation, are essential when working with this substance. Storage should be in a cool, well-ventilated area, away from heat, sparks, open flames, and oxidizing agents, preferably under an inert gas atmosphere to prevent air sensitivity issues.


For industries seeking a reliable supply of high-quality N,N'-Dimethyl-1,3-propanediamine (CAS 111-33-1), securing a reputable manufacturer and supplier is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing this essential chemical, adhering to stringent quality control standards to ensure purity and consistency. For those looking to buy or purchase this compound, competitive price options and flexible supply solutions are available. Enquiries regarding bulk orders or specific grade requirements are welcome, ensuring that your industrial needs for this crucial chemical are met with professionalism and efficiency.

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