The field of advanced organic chemistry continually introduces novel compounds that are instrumental in the development of cutting-edge technologies and pharmaceuticals. Among these, benzocarbazole derivatives have garnered significant attention for their versatile applications, particularly as intermediates in the pharmaceutical industry. For professionals in R&D and procurement, understanding the sourcing and specifications of these complex molecules is crucial. This guide focuses on 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile (CAS 1256584-80-1), a key compound that exemplifies the importance of specialized chemical suppliers.

Understanding Benzocarbazole Derivatives in Pharma

Benzocarbazoles, characterized by their fused ring systems, offer unique structural properties that make them valuable in medicinal chemistry. The specific derivative, 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, is a sophisticated intermediate widely recognized for its role in the synthesis of Anaplastic Lymphoma Kinase (ALK) inhibitors, such as Alectinib. These inhibitors are critical in targeted cancer therapies, particularly for patients with specific genetic mutations driving tumor growth. The high purity (often 98%) and precise molecular structure of this compound are essential for ensuring the efficacy and safety of the final drug product. As a white powder, it is suitable for various chemical reactions and formulations.

Where to Buy: Identifying Key Manufacturers and Suppliers

For businesses looking to buy CAS 1256584-80-1, identifying reputable manufacturers and suppliers is the first step. The global chemical market includes numerous players, but specializing in high-value pharmaceutical intermediates requires specific expertise and quality control measures. China has emerged as a significant hub for fine chemical manufacturing, boasting companies that offer competitive pricing and large-scale production capabilities. When evaluating suppliers, it is prudent to consider:

• Product Catalog Depth: Does the manufacturer offer a range of related intermediates or building blocks?
• Technical Data: Availability of detailed product information, including spectra (NMR, HPLC) and Certificates of Analysis (CoA).
• Customer Service: Responsiveness to inquiries, clarity on pricing, payment terms (T/T, L/C, PayPal), and shipping (FOB, CIF, EXW).
• Supply Chain Reliability: Consistent quality, on-time delivery, and adherence to international shipping standards.

Many suppliers will clearly state their contact information and offer services like custom synthesis for specific client needs. Actively seeking out these manufacturers, especially those with a focus on pharmaceutical intermediates, will simplify the procurement process and ensure a stable supply for your research or production needs.

Procurement Considerations and Market Trends

When procuring 9-ethyl-8-iodo-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile, buyers should be prepared to discuss volume requirements and pricing. Manufacturers often provide tiered pricing based on quantity, making bulk purchases more economical. Furthermore, understanding the transportation logistics, including port of origin (e.g., Shanghai, Qingdao) and transit times, is vital for planning production schedules. The demand for advanced pharmaceutical intermediates is projected to grow as targeted therapies continue to evolve, making it a strategic advantage to establish relationships with reliable suppliers early on. By carefully considering these factors, procurement managers can ensure they buy this essential benzocarbazole derivative from a trusted source, supporting their critical drug development initiatives.