In the realm of chemical synthesis, certain compounds stand out for their versatility and indispensable role in creating more complex molecules. 4-Chloro-4'-hydroxybenzophenone, identified by its CAS number 42019-78-3, is one such compound. Widely recognized in both the chemical and pharmaceutical industries, it serves as a crucial intermediate, most notably in the production of Fenofibrate, a vital medication for managing hyperlipidemia. This article delves into its fundamental chemical and physical properties, its manufacturing considerations, and its broader applications that make it a valuable commodity for industries worldwide.

The chemical identity of 4-Chloro-4'-hydroxybenzophenone is defined by its molecular formula C13H9ClO2 and a molecular weight of 232.662 g/mol. Physically, it typically appears as a white to light brown crystalline powder, a characteristic that is essential for its handling and identification. Its melting point, usually within the range of 177-181 °C, signifies its solid state at ambient temperatures and contributes to its stability. The compound's boiling point is notable, indicating its resilience under higher thermal conditions. These properties are not merely academic; they are critical for manufacturers in China and other global suppliers who prioritize precision and consistency in their chemical intermediates. The assay level, often greater than 98.0%, further reinforces its suitability for applications demanding high purity, such as in pharmaceutical manufacturing.

The most prominent application of 4-Chloro-4'-hydroxybenzophenone is its function as a key intermediate in the synthesis of Fenofibrate. Fenofibrate is a fibrate drug that helps manage cholesterol and triglyceride levels, playing a crucial role in cardiovascular health. The unique chemical structure of 4-Chloro-4'-hydroxybenzophenone, featuring both a reactive chloro group and a hydroxy group, makes it an ideal starting material for the complex synthetic routes required to produce Fenofibrate. This direct link to a significant pharmaceutical product underscores its importance in the medicinal chemistry landscape and the global pharmaceutical supply chain. The ability to efficiently buy 4-Chloro-4'-hydroxybenzophenone is therefore critical for drug manufacturers.

Manufacturing this compound involves precise chemical engineering to ensure the desired purity and crystalline form. It is commonly supplied in 25 kg drums, with suppliers offering customization options to meet specific client needs. Proper storage is also essential to maintain its quality; it should be kept in a cool, ventilated place, protected from heat and moisture. These manufacturing and storage considerations are fundamental for suppliers aiming to provide reliable chemical intermediates. For businesses seeking a consistent supply, partnering with experienced manufacturers in China is often a strategic choice, given their capacity and adherence to quality standards.

Beyond its pharmaceutical applications, 4-Chloro-4'-hydroxybenzophenone holds potential in other areas of organic chemistry. Its reactive nature allows for the development of various benzophenone derivatives, which are utilized in applications such as UV stabilizers, photointiators, and other specialty chemicals. Researchers and chemical engineers exploring novel materials and synthetic pathways find this compound to be a valuable asset due to its adaptability. As industries continue to demand innovative chemical solutions, the role of reliable intermediates like 4-Chloro-4'-hydroxybenzophenone remains indispensable, driving progress in both chemical science and product development.

At NINGBO INNO PHARMCHEM CO.,LTD., we are dedicated to providing high-quality chemical intermediates, including 4-Chloro-4'-hydroxybenzophenone. Our commitment to excellence in research, development, and production ensures that our clients receive products that meet rigorous standards, supporting their advancements in pharmaceuticals and other chemical industries.