NINGBO INNO PHARMCHEM CO.,LTD. is pleased to announce its offering of high-quality Tert-Butylmagnesium Chloride, a crucial reagent widely utilized in modern organic synthesis. This compound, identified by CAS Number 677-22-5, belongs to the important class of Grignard reagents.

Tert-Butylmagnesium Chloride has a molecular formula of C4H9MgCl and a molecular weight of 116.87 g/mol. It is typically supplied as a solution, commonly presented as a colorless to light yellow liquid in solvents such as tetrahydrofuran (THF) or diethyl ether. Standard concentrations range from 1.0 M to 2.0 M in THF, providing chemists with flexible options for their synthetic procedures.

The unique structure of Tert-Butylmagnesium Chloride, featuring a sterically hindered tert-butyl group, imparts distinct reactivity characteristics compared to less bulky Grignard reagents. This steric effect influences its nucleophilicity and basicity, making it particularly valuable for selective reactions. It is often preferred for additions to sensitive electrophiles or when seeking to minimize side reactions like enolization. Despite its somewhat reduced nucleophilicity compared to linear alkyl Grignards, it remains a powerful tool for forming carbon-carbon bonds.

Handling Tert-Butylmagnesium Chloride requires significant precautions due to its highly reactive nature. It is known to be pyrophoric, meaning it can ignite spontaneously upon exposure to air. Furthermore, it is extremely sensitive to moisture and reacts violently with water and oxygen. Consequently, stringent inert atmosphere conditions, typically under nitrogen or argon, are mandatory during storage and handling procedures. Recommended storage conditions involve maintaining the product at low temperatures, usually between 2-8°C, in flame-proof containers to ensure stability and prevent decomposition.

The applications of Tert-Butylmagnesium Chloride are extensive across various chemical disciplines. It is a cornerstone reagent in selective Grignard reactions, enabling the efficient formation of new carbon-carbon bonds, which are fundamental to constructing complex organic molecules. Its ability to introduce the tert-butyl group is particularly useful in target molecule synthesis. Significant applications are found in the synthesis of pharmaceutical intermediates, where the precise and selective nature of its reactions is critical for developing active pharmaceutical ingredients (APIs). It also plays a role in the production of specialty chemicals and is occasionally employed in polymer chemistry research and manufacturing.

The demand for high-purity Tert-Butylmagnesium Chloride continues to grow as synthetic chemists push the boundaries of molecular complexity. Its reliable performance in demanding reactions makes it an indispensable asset in research and industrial production settings. Ensuring the quality and consistency of the product is paramount for achieving reproducible results and high reaction yields, especially in large-scale manufacturing processes. A trusted supplier is essential for accessing this sensitive and important reagent.

For researchers and manufacturers seeking a dependable source for this vital chemical, finding a qualified Tert-Butylmagnesium Chloride manufacturer is a key step. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier providing high-quality Tert-Butylmagnesium Chloride solution suitable for various synthetic applications. Prospective customers interested in obtaining a quote for the Tert-Butylmagnesium Chloride price are encouraged to contact us directly. Whether you need to buy Tert-Butylmagnesium Chloride for pilot studies or purchase Tert-Butylmagnesium Chloride in bulk quantities for commercial production, NINGBO INNO PHARMCHEM is committed to meeting your requirements with a reliable product and professional service.