NINGBO INNO PHARMCHEM CO.,LTD. is pleased to announce the availability of high-quality Tetrahydrofuran, commonly known as THF. This essential chemical compound, identified by its CAS Number 109-99-9 and chemical formula C4H8O, is a cornerstone ingredient across numerous industrial and pharmaceutical applications. Recognized by several names including oxacyclopentane, 1,4-butyloxide, and tetramethylene oxide, THF is a key member of the ether class of organic compounds, representing the complete hydrogenation product of furan.

At room temperature, Tetrahydrofuran presents as a colorless, volatile liquid. It is easily distinguishable by its characteristic odor, which is often described as similar to diethyl ether. One of its most valuable properties is its exceptional solubility. THF readily dissolves in water, as well as a wide range of organic solvents including ethanol, ether, acetone, and benzene. This broad solubility profile has earned it the moniker of a "universal solvent," highlighting its utility in dissolving many substances that are not soluble in more common solvents.

The physical properties of THF are well-defined and critical for its applications. It possesses a low flash point of approximately -14.7 °C (-14 °C in some reports), categorizing it as a highly flammable substance, which necessitates careful handling and storage. Its boiling point is around 66 °C, while its melting and freezing points are significantly lower, approximately -108.4 °C to -108.5 °C. The density of THF is about 0.8892 g/cm3 at 20 °C. Purity is paramount for its industrial uses, with typical specifications reaching 99.9% minimum. These precise physical and chemical characteristics ensure its reliability in demanding processes.

The applications of Tetrahydrofuran are remarkably diverse, underscoring its importance in the chemical industry. As a solvent, it is particularly effective for dissolving challenging polymers such as polyvinyl chloride (PVC), polyvinylidene chloride, and butyl aniline. This makes it an invaluable component in surface coatings, where it helps create smooth and durable finishes. Its solvent power is also harnessed in the formulation of anti-corrosion coatings, printing inks, adhesive tapes, and film coatings, providing excellent adhesion and dispersion properties.

Beyond its role as a solvent, THF is a vital raw material and intermediate in various organic synthesis processes. It serves as a crucial intermediate in the production of nylon, a widely used synthetic polymer. It is also employed in the synthesis of pesticide phenylbutyltin. Furthermore, THF is a precursor for the synthesis of a range of important chemicals, including adipic nitrile, adipic acid, adipic diamine, succinic acid, and butanediol, as well as γ-butyrolactone. These downstream products are essential building blocks for numerous industries.

Tetrahydrofuran plays a significant role in the manufacturing of various synthetic materials. It is directly used in the production of synthetic fibers, synthetic resins, and synthetic rubbers, contributing to the creation of materials with specific desired properties. It is also essential in the creation of precision tapes and finds application as a solvent in the electroplating industry, where its presence in aluminum electroplating solutions allows for precise control over the thickness and brightness of the deposited aluminum layer.

The pharmaceutical industry benefits significantly from the use of Tetrahydrofuran. It functions as a versatile medicinal solvent, assisting in the synthesis, purification, and formulation of various pharmaceutical compounds. Specific examples mentioned where THF is utilized include the production or processing of Kebiqing, progesterone, and rifampicin. Its ability to dissolve a wide range of organic compounds and its relatively low boiling point (allowing for easy removal after reaction or purification) make it suitable for pharmaceutical manufacturing processes.

Given its flammable nature and susceptibility to oxygen oxidation (which can lead to peroxide formation), the storage and handling of Tetrahydrofuran require strict adherence to safety protocols. It should be stored in tightly closed containers made of suitable materials like glass bottles or stainless steel, as THF can potentially deform or dissolve certain plastic containers. Storage conditions should involve low temperatures, ideally not exceeding 29°C, and the storage area must be kept away from sources of ignition, heat, and incompatible materials such as oxidizing agents, acids, and bases. Segregated storage is essential to prevent unintended reactions. Storage areas should be equipped with explosion-proof lighting and ventilation facilities. The use of mechanical equipment or tools that could generate sparks should be prohibited. Additionally, appropriate leakage emergency treatment equipment and containment materials should be readily available in storage areas.

NINGBO INNO PHARMCHEM CO.,LTD. supplies Tetrahydrofuran in various packaging options to suit different industrial needs. Standard packaging includes steel drums with a net weight of 180kg. Other options may include ISO Tanks, IBC Drums, and Flexitanks, providing flexibility for bulk transportation. A 20ft container typically loads approximately 14.4 metric tons when packed in steel drums. Our commitment is to provide high-purity THF, essential for critical applications ranging from pharmaceutical synthesis to polymer production.

As a reliable manufacturer and supplier of Tetrahydrofuran, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing quality products and dependable service. We understand the importance of a consistent and secure supply chain for our customers. For inquiries regarding the price of Tetrahydrofuran, options to buy, or detailed information about purchasing this versatile solvent and intermediate, prospective customers are encouraged to contact us directly. We offer competitive pricing and efficient delivery timelines, typically within 7-15 days after receiving the necessary payment terms, such as T/T deposit or L/C original. We aim to be your trusted partner for all your Tetrahydrofuran requirements, ensuring you receive a product that meets stringent quality standards for your demanding applications. Discover how to purchase bulk quantities and discuss your specific needs with our sales team.