Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to understanding and providing the science behind our products. Praziquantel, a crucial anthelmintic, operates through a fascinating praziquantel mechanism of action that makes it highly effective against a range of parasitic flatworms. Unlike many other antiparasitics, Praziquantel's primary mode of action involves inducing rapid and sustained muscle contraction in susceptible parasites. This is achieved by increasing the parasite cell membrane's permeability to calcium ions. The influx of calcium ions causes tetanic contractions of the parasite's musculature, leading to paralysis.
This paralysis is critical for the drug's efficacy. The contracted parasites are effectively dislodged from their position within the host's tissues or blood vessels. In the case of schistosomiasis, this means they are moved from the mesenteric or vesical venules to the liver circulation, where they are subsequently destroyed by the host's immune system. For cestodes (tapeworms), the disruption of their tegument and subsequent paralysis allows the host's digestive enzymes to break them down.
The significance of this mechanism cannot be overstated, especially when considering the praziquantel for schistosomiasis application. Its ability to rapidly neutralize the parasites prevents further damage and allows the host's body to clear the infection. This makes it an invaluable tool in treating debilitating diseases. For healthcare professionals and researchers looking to buy bulk praziquantel powder online, understanding this mechanism ensures the proper application of the drug.
NINGBO INNO PHARMCHEM CO.,LTD. supplies Praziquantel that is manufactured to the highest purity standards, ensuring that the active compound functions as intended. The detailed knowledge of praziquantel side effects and interactions further aids in its safe and effective therapeutic application. As a provider of this essential medicine, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to supporting global health efforts through scientifically sound and high-quality pharmaceutical ingredients.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
