Nystatin Powder stands as a highly effective pharmaceutical material, widely recognized for its potent antifungal properties. As an essential active pharmaceutical ingredient (API), it plays a crucial role in combating a diverse range of fungal and yeast infections, particularly those affecting the skin and mucous membranes. Produced under stringent quality controls, this fine powder ensures reliability and efficacy for various medical applications.

The mechanism of action of Nystatin Powder is centered on its nature as a polyene antifungicin. It primarily targets fungi by binding to sterols, a vital component of fungal cell membranes. This specific interaction leads to a significant alteration in the cell membrane's permeability, causing important cellular contents to leak out. This disruption effectively inhibits fungal activity and growth, leading to the eradication of the infection. It is important to note that Nystatin is a highly selective antifungal agent, exhibiting no inhibitory effects on bacteria or viruses, thus providing targeted therapeutic action.

Nystatin Powder's broad spectrum of antifungal activity makes it particularly effective against Candida species, including the most common culprit, Candida albicans. This versatility allows for its application in treating a variety of cutaneous and mucocutaneous mycotic infections. Common conditions where Nystatin Powder is extensively used include intertrigo (rash in skin folds), diaper rash in infants, jock itch, athlete's foot, and ringworm. Its powdered form is especially advantageous for use in moist body areas, as it helps to keep the skin dry while delivering its therapeutic effect, promoting a healthier environment for skin recovery.

Ensuring the highest standards, Nystatin Powder conforms to major pharmacopoeia requirements such as BP, USP, and EP, guaranteeing its pharmaceutical grade quality. With a typical purity of 99%, it reflects a commitment to excellence in pharmaceutical manufacturing. The physical properties, including a melting point of over 155°C, a solubility of 0.36g/L, and a density of 1.27 g/mL at 25°C, further attest to its consistent and reliable characteristics. These attributes are critical for its integration into various pharmaceutical formulations.

For optimal results, Nystatin Powder is intended for external topical use only. Patients should thoroughly clean and dry the affected area before applying a thin, uniform layer of the powder. The typical dosage involves application two to three times daily, or as directed by a healthcare professional. For fungal infections of the feet, it is also advisable to dust the powder into socks and shoes to prevent re-infection and promote a dry environment. It is crucial to complete the full course of treatment, even if symptoms show significant improvement, to ensure the complete eradication of the infection and prevent recurrence. Accidental contact with eyes or mucous membranes should be avoided. While generally well-tolerated, minor side effects such as local irritation, burning, or rash at the application site may occur, but serious allergic reactions are rare. Storage is straightforward: keep the container tightly closed at room temperature, ideally between 20-25°C (68-77°F), away from excessive heat and moisture, to preserve its two-year shelf life.

For pharmaceutical companies and formulators globally, sourcing a high-quality Nystatin Powder is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and supplier of this critical antifungal API, ensuring product integrity and competitive price points. Whether you intend to buy in bulk or purchase specific quantities for your production needs, reliability and adherence to international standards are guaranteed. Our commitment is to provide pharmaceutical raw materials that meet the rigorous demands of the global healthcare industry.