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Octocrylene (CAS 6197-30-4): A Key UV Filter in Modern Skincare

Octocrylene, identified by its CAS number 6197-30-4 and chemical formula C24H27NO2, stands as a pivotal organic UV filter in the cosmetic and personal care industries. This oil-soluble, colorless to light yellow oily liquid is primarily celebrated for its ability to absorb a broad spectrum of ultraviolet radiation, specifically targeting UVB rays and shorter UVA rays. Its molecular weight is 361.48, and its distinct chemical structure, a cinnamate derivative, enables it to efficiently absorb UV photons and dissipate the energy as harmless heat, thereby preventing sun damage to the skin.


The primary role of Octocrylene in formulations, particularly sunscreens, is to protect the skin from the harmful effects of sun exposure. This includes guarding against sunburn, reducing the risk of premature aging such as wrinkles and leathery skin, and helping to decrease the overall risk of skin cancer. Beyond its direct UV absorption capabilities, Octocrylene is highly valued for its exceptional photostability. Unlike some other UV filters that can degrade rapidly when exposed to sunlight, Octocrylene maintains its integrity and effectiveness for prolonged periods. This characteristic also makes it an excellent stabilizer for other UV-sensitive ingredients, notably Avobenzone, which is crucial for achieving comprehensive UVA protection. Its oil-soluble nature further enhances the water resistance of sunscreen products, making them ideal for outdoor and water-based activities.


While Octocrylene is widely utilized and generally considered safe at concentrations up to 10% in the European Union and the United States, ongoing scientific discussions address certain concerns. Some individuals, particularly those with sensitive skin or a history of reactions to topical anti-inflammatory drugs like ketoprofen, may experience skin irritation or photoallergic reactions. Research indicates that Octocrylene can be absorbed through the skin, enter the bloodstream, and be metabolized before excretion. A more significant concern revolves around its potential to degrade over time into benzophenone, a compound suspected of being a carcinogen and an endocrine disruptor. This degradation process has been observed in commercial sunscreen products, with benzophenone levels potentially increasing during storage.


The environmental impact of Octocrylene has also drawn considerable attention. It is not classified as reef-safe, as studies have shown it can accumulate in marine organisms, including fish and corals. This accumulation is linked to adverse effects such as DNA damage, developmental abnormalities, and mitochondrial dysfunction in aquatic life, contributing to phenomena like coral bleaching. Consequently, certain regions, including Palau, Hawaii, and the U.S. Virgin Islands, have implemented bans on the sale of products containing Octocrylene to protect their delicate marine ecosystems. These environmental considerations prompt formulators to carefully evaluate their ingredient choices and seek sustainable alternatives where feasible.


For manufacturers and suppliers of cosmetic raw materials, ensuring product quality and adhering to regulatory standards is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-purity Octocrylene (CAS 6197-30-4) that meets stringent industry specifications. We understand the complexities surrounding cosmetic ingredients and strive to offer products that enable our partners to create effective and safe formulations. When considering where to buy Octocrylene or looking for a reliable Octocrylene supplier, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted Octocrylene manufacturer dedicated to quality. For competitive Octocrylene price inquiries or to purchase Octocrylene in bulk, we invite you to connect with our sales team to discuss your specific requirements.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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