Ombitasvir, also widely known by its development code ABT-267, with the CAS number 1258226-87-7, stands as a cornerstone in the modern therapeutic landscape for hepatitis C virus (HCV) infection. As a highly potent and selective inhibitor of the HCV non-structural protein 5A (NS5A), Ombitasvir plays a critical role in the direct-acting antiviral (DAA) regimens that have revolutionized the treatment of this global health challenge.
The efficacy of Ombitasvir is rooted in its remarkable antiviral activity. In vitro studies have demonstrated its picomolar potency and broad pan-genotypic activity, making it effective against a wide range of HCV genotypes. Specifically, Ombitasvir exhibits impressive 50% effective concentrations (EC50s) ranging from 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a. This broad-spectrum effectiveness underscores its value in developing comprehensive treatment strategies.
Clinically, Ombitasvir gained significant attention following its approval by the U.S. Food and Drug Administration (FDA) in 2015. It is a key component of combination therapies, notably in products such as Viekira Pak and Technivie. In Viekira Pak, Ombitasvir is co-formulated with paritaprevir, ritonavir, and dasabuvir, offering a powerful interferon-free regimen for patients with genotype 1 chronic hepatitis C virus infection, including those with compensated cirrhosis. Similarly, in Technivie, combined with paritaprevir and ritonavir, it addresses genotype 4 chronic HCV infection without cirrhosis. These combinations highlight Ombitasvir’s crucial contribution to highly effective, all-oral DAA treatments that significantly improve patient outcomes and simplify treatment protocols compared to older, interferon-based therapies.
NINGBO INNO PHARMCHEM CO.,LTD. is proud to be a leading manufacturer and supplier of high-quality Ombitasvir (ABT-267). Our commitment to excellence ensures that every batch of Ombitasvir meets stringent quality standards, providing a product that is consistently white crystalline powder with an assay purity of more than 99%. This dedication to purity and consistency is vital for pharmaceutical applications, where the active pharmaceutical ingredient's integrity directly impacts drug efficacy and patient safety. Our state-of-the-art manufacturing facilities and robust quality control systems guarantee the reliability and performance required by the global pharmaceutical industry.
For pharmaceutical companies and research institutions looking to buy or purchase Ombitasvir (ABT-267), NINGBO INNO PHARMCHEM CO.,LTD. offers a reliable source with a competitive price. As a trusted supplier, we understand the critical importance of a stable and high-quality supply chain. Whether you require small quantities for research and development or bulk orders for large-scale production, our team is equipped to handle your needs efficiently and professionally. We invite potential partners to inquire about the price of our Ombitasvir (ABT-267) and experience the benefits of working with a dedicated and customer-focused manufacturer. Our aim is to foster long-term partnerships by delivering superior products and unparalleled service, ensuring that the essential active pharmaceutical ingredients for life-saving medications are readily available.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
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