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In the realm of pharmaceutical development, the optimization of oral solid dosage forms (OSDDs) is a continuous pursuit. At NINGBO INNO PHARMCHEM CO.,LTD., we recognize that achieving desired therapeutic outcomes hinges on critical factors such as disintegration and dissolution rates. This is where the expertise in superdisintegrant properties of CCS becomes invaluable. Croscarmellose Sodium (CCS) has emerged as a premier choice for formulators aiming to enhance the performance of tablets and capsules.
The efficacy of many oral medications is directly linked to how quickly and completely they disintegrate in the body. Croscarmellose Sodium, as a chemically modified cellulose derivative, is engineered for superior performance in this regard. Unlike conventional disintegrants, CCS offers rapid water uptake and remarkable swelling capacity. This inherent characteristic allows it to act efficiently as a 'wick,' drawing gastrointestinal fluids into the tablet matrix. As the CCS particles swell, they exert mechanical force, breaking apart the tablet structure and exposing the active pharmaceutical ingredients (APIs) for absorption.
The impact of Croscarmellose Sodium on drug bioavailability cannot be overstated. By ensuring swift disintegration, it accelerates the release of the API, allowing for a greater proportion to enter the bloodstream. This improved absorption can lead to faster onset of action and potentially reduced dosing requirements, enhancing the overall therapeutic profile of the medication. Formulators often consider enhancing drug bioavailability with croscarmellose sodium as a key strategy in drug development.
Moreover, the versatility of CCS in various manufacturing processes makes it a preferred excipient. It performs exceptionally well in direct compression, a streamlined manufacturing method that avoids granulation steps. Its excellent flow properties and compressibility ensure uniform tablet weight and hardness. Equally, in wet granulation, CCS integrated either intragranularly or extragranularly, consistently aids in achieving rapid tablet breakup. This dual capability simplifies process development and reduces manufacturing complexities.
NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing high-quality Croscarmellose Sodium that meets rigorous pharmaceutical standards. By understanding and utilizing the unique attributes of this pharmaceutical grade croscarmellose sodium, manufacturers can develop more effective and reliable oral solid dosage forms, ultimately benefiting patient health.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
