P-Toluene Sulfonyl Chloride (PTSC), identified by its CAS Number 98-59-9, is a crucial organic compound renowned for its extensive applications across various industries. With a molecular formula of C7H7ClO2S and a molecular weight of 190.65, PTSC typically appears as a clear liquid, though it can also be found as a white crystal powder, maintaining a high assay of 99% minimum purity.

This versatile chemical serves as a cornerstone in numerous synthetic processes. Its primary role as an intermediate is widely recognized in the production of various dyes, including disperse dyes, ice dyes, and acid dyes, contributing to the vibrant palette of modern industries. Beyond coloration, PTSC is indispensable in the pharmaceutical sector. It plays a vital part in the synthesis of drugs like metsulfuron, a herbicide with pharmaceutical applications, and is a key intermediate in the synthesis of paroxetine, a selective serotonin reuptake inhibitor (SSRI) medication used for mood disorders such as major depressive disorder, obsessive-compulsive disorder, and generalized anxiety disorder.

In the realm of organic synthesis, PTSC is highly valued for its ability to convert hydroxyl groups into excellent leaving groups, known as tosylates. This transformation is pivotal for facilitating subsequent nucleophilic substitution (SN2) and elimination (E2) reactions, which are fundamental in creating complex organic molecules. The reaction often occurs in the presence of a weak base like pyridine, which effectively neutralizes the hydrochloric acid byproduct, ensuring reaction efficiency and product purity. Moreover, PTSC acts as a dehydrating agent in specific conversions, such as urea to carbodiimide, and is employed as an analytical reagent in laboratories for the determination of primary, secondary, and tertiary amines.

The utility of PTSC extends to several other specialized applications. It functions as a flow-promoting agent in paints, enhancing their application properties, and serves as an adhesive and plasticizer for polyamides, contributing to material flexibility and durability. Furthermore, it is utilized in nitrocellulose formulations, coating materials, and as an antistatic agent. Its role as a gloss enhancer in plastic film preparations and a basic material in electroplating solutions underscores its broad industrial relevance.

Given its reactive nature, proper handling and storage of P-Toluene Sulfonyl Chloride are paramount. It is moisture sensitive and incompatible with strong oxidizing agents and strong bases. Therefore, it must be stored in a well-ventilated warehouse, away from open flames and high temperatures, and kept separate from oxidants and acids to maintain its stability and efficacy.

As a leading P-Toluene Sulfonyl Chloride manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to delivering high-quality PTSC that meets stringent industry standards. For those looking to buy P-Toluene Sulfonyl Chloride, understanding its diverse applications from dye synthesis to advanced pharmaceutical intermediates is key. We offer competitive P-Toluene Sulfonyl Chloride price options and ensure reliable supply for your industrial and research needs. Whether you are seeking to purchase P-Toluene Sulfonyl Chloride for bulk manufacturing or specific laboratory applications, our expertise ensures you receive a product of superior quality, supporting your innovation and production processes.