P-Toluenesulfonic Anhydride (PTSA Anhydride), identified by its Chemical Abstracts Service (CAS) number 4124-41-8, stands as a highly significant compound in the realm of organic chemistry. With a molecular formula of C14H14O5S2 and a molecular weight of approximately 326.38, this chemical is widely recognized for its robust reactivity and broad utility across various industrial and research applications.

This versatile substance typically appears as a white to off-white powder, crystal, or block. Its key physical properties include a melting point ranging from 121-127 °C and a predicted boiling point of around 478 °C. It is known to hydrolyze in water but exhibits good solubility in many organic solvents, making it adaptable for diverse reaction environments. Due to its moisture-sensitive nature, proper storage in a cool, dry place under an inert atmosphere, ideally at 2-8 °C, is crucial to maintain its stability and efficacy.

The applications of P-Toluenesulfonic Anhydride are extensive and critical. Primarily, it serves as a powerful organic intermediate and a reliable reagent for tosylation, a fundamental reaction in organic synthesis. It is particularly effective for the tosylation of nucleophiles, such as alcohols, offering a "softer" electrophilic alternative to p-toluenesulfonyl chloride. This compound also functions as an efficient catalyst in a wide array of chemical transformations, including esterification, acetylation, and alkylation reactions. Its utility extends to acting as an additive in palladium-catalyzed allylic alkenylation of allylic alcohols and activating 2-deoxy-sugar hemiacetals for stereoselective reactions.

Beyond its role in basic synthesis, P-Toluenesulfonic Anhydride is indispensable in several key industries. In the pharmaceutical sector, it is a crucial ingredient and catalyst in the production of various drugs, including antibiotics and anti-inflammatory medicines, and also acts as a stabilizer in pharmaceutical products. The agrochemical industry utilizes it in the manufacturing of herbicides, insecticides, and fungicides, enhancing the synthesis of active ingredients. Furthermore, PTSA Anhydride plays a significant part in the production of dyes, pigments, and various polymers such as nylon, polyester, and polyurethane, where it acts as a polymerization catalyst, contributing to the creation of high-quality materials.

Additional applications span from its use in laboratories for the purification of organic compounds, as a desiccant, and as a drying agent, to more specialized roles as a corrosion inhibitor and a surfactant in electroplating processes. Its involvement in the fragrance, flavor, and oil refining industries further underscores its widespread importance.

For those seeking a dependable manufacturer and supplier of high-quality P-Toluenesulfonic Anhydride, NINGBO INNO PHARMCHEM CO.,LTD. offers a product that meets stringent quality standards, often available with certificates and detailed reports. Our commitment ensures a reliable supply of this essential chemical for your various needs. To inquire about the price or to buy / purchase P-Toluenesulfonic Anhydride, please contact us for a competitive quote. We provide product documents and samples upon request, ensuring transparency and satisfaction for our global clientele. Our packaging typically involves 25KG drums, designed to maintain product integrity during shipping and storage.