Hydrogenated Palm Oil, identified by its CAS number 68514-74-9, stands as a vital component within the pharmaceutical industry. Sourced from palm oil and subjected to controlled hydrogenation, this material is processed to meet stringent pharmaceutical grade standards, including GMP, FDA, and USP. It functions primarily as a highly versatile excipient, playing numerous critical roles in the formulation and manufacturing of medicinal products. Its properties make it indispensable for achieving desired physical characteristics, stability, and performance in various dosage forms. As a pharmaceutical ingredient, its quality and consistency are paramount, ensuring safety and efficacy in the final drug product.
One of the primary applications of Pharmaceutical Grade Hydrogenated Palm Oil CAS 68514-74-9 is its use as a foundational excipient in a wide array of drug formulations. It serves as an inactive ingredient that provides bulk, structure, and functional properties to dosage forms such as capsules, ointments, creams, and suppositories. In solid dosage forms like tablets and capsules, it can act as a diluent, filler, binder, or flow aid, facilitating manufacturing processes and ensuring content uniformity. In semi-solid and liquid preparations, it contributes to the consistency, texture, and stability of the formulation, forming bases for creams, ointments, or suppositories.
Beyond its basic excipient functions, Hydrogenated Palm Oil CAS 68514-74-9 is increasingly utilized in advanced drug delivery systems, particularly in creating sustained-release formulations. Its solid or semi-solid nature at specific temperatures allows it to form a matrix or barrier that controls the dissolution and diffusion rate of the active pharmaceutical ingredient (API). By embedding the API within a matrix of hydrogenated palm oil, manufacturers can engineer formulations that release the drug gradually over an extended period. This results in prolonged therapeutic effect, reduced dosing frequency, improved patient compliance, and potentially minimized side effects associated with fluctuating drug levels.
Furthermore, this pharmaceutical grade material contributes to the solubility enhancement of poorly water-soluble drugs. While hydrogenated fats themselves are hydrophobic, they can improve the *dispersion* or *presentation* of lipophilic or poorly soluble APIs within a formulation context. Acting as a carrier or a component within lipid-based systems, Hydrogenated Palm Oil CAS 68514-74-9 can facilitate the wetting and dissolution of the API in the gastrointestinal tract or at the site of absorption. This is particularly relevant in formulations where the excipient is melted during processing or digestion, releasing the API in a more bioavailable form or facilitating its absorption.
In emulsion formulations, Hydrogenated Palm Oil CAS 68514-74-9 can function as an effective emulsifying agent or contribute to the stability of the emulsion system. Emulsions, common in creams, lotions, and some liquid oral formulations, require stable dispersion of immiscible phases (oil and water). As a lipid-based component, hydrogenated palm oil can help reduce interfacial tension and stabilize the dispersed phase, preventing phase separation over time. Its properties contribute to the desired consistency and texture of the emulsion, ensuring product homogeneity and performance throughout its shelf life.
The manufacturing process of solid dosage forms, such as tablets, significantly benefits from the lubricating properties of Hydrogenated Palm Oil CAS 68514-74-9. In tablet compression, friction between the powder mixture and the tablet press machinery (dies and punches) can cause sticking, capping, and other production issues. Incorporating a small amount of hydrogenated palm oil into the blend acts as a lubricant, reducing friction and allowing for smooth ejection of the compressed tablet. This improves manufacturing efficiency, reduces wear and tear on equipment, and results in tablets with smooth surfaces and consistent weight and hardness.
Lastly, Pharmaceutical Grade Hydrogenated Palm Oil CAS 68514-74-9 finds extensive use in topical pharmaceutical formulations, including creams, ointments, and lotions. Its lipid nature provides emollient and occlusive properties when applied to the skin. As an emollient, it helps to soften and smooth the skin; as an occlusive agent, it forms a protective barrier on the skin surface, reducing transepidermal water loss and promoting skin hydration. This makes it an excellent base for dermatological preparations, improving skin feel and potentially enhancing the percutaneous absorption of co-formulated APIs.
Ensuring the highest quality is paramount for pharmaceutical excipients. Pharmaceutical Grade Hydrogenated Palm Oil CAS 68514-74-9 supplied by NINGBO INNO PHARMCHEM CO.,LTD. meets rigorous international standards, including compliance with GMP (Good Manufacturing Practices), FDA guidelines, and USP monographs where applicable. This commitment to quality guarantees that the material is pure, consistent, and suitable for its intended use in drug manufacturing, providing reliability for pharmaceutical manufacturers worldwide.
Acquiring high-quality Pharmaceutical Grade Hydrogenated Palm Oil CAS 68514-74-9 is crucial for pharmaceutical companies aiming for product excellence. NINGBO INNO PHARMCHEM CO.,LTD. is a trusted supplier and manufacturer offering this essential excipient. For those looking to source this material, inquiries regarding product specifications, pricing, and availability are welcomed. You can reliably buy or purchase Hydrogenated Palm Oil CAS 68514-74-9 from a reputable manufacturer dedicated to providing pharmaceutical-grade ingredients. Understanding the correct price and minimum order quantities is straightforward when dealing directly with a primary supplier. If you are a manufacturer searching for a dependable source or looking to understand the current market price, contacting a professional supplier is the best approach. NINGBO INNO PHARMCHEM CO.,LTD. offers competitive pricing and flexible options to purchase the required quantities of this key pharmaceutical excipient.
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