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Apixaban, identified by its CAS number 503612-47-3, is a highly effective anticoagulant with a well-defined pharmacological profile. Its primary mechanism of action as a direct, selective, and orally active inhibitor of Factor Xa is fundamental to its therapeutic success. This inhibition disrupts the coagulation cascade, leading to reduced thrombin generation and, consequently, diminished blood clot formation. NINGBO INNO PHARMCHEM CO.,LTD. provides this crucial pharmaceutical ingredient, enabling its widespread clinical application.
The clinical significance of Apixaban is vast, particularly in preventing stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AFib). Its efficacy in this context, coupled with a generally favorable safety profile compared to older anticoagulants, has made it a preferred choice for many healthcare providers. Furthermore, Apixaban is critical in treating established deep vein thrombosis (DVT) and pulmonary embolism (PE), and in reducing the risk of their recurrence, thereby improving patient outcomes and quality of life.
The pharmacokinetic properties of Apixaban, including its absorption, metabolism, and excretion, contribute to its predictable anticoagulant effect. These properties are thoroughly studied and form the basis for dosage recommendations. Pharmaceutical companies relying on Apixaban API from suppliers like NINGBO INNO PHARMCHEM CO.,LTD. depend on consistent quality to ensure these pharmacokinetic profiles are maintained in the final drug product.
In addition to its direct therapeutic applications, Apixaban serves as a valuable reference compound in pharmacological research. Its potent and selective inhibition of Factor Xa makes it an essential tool for exploring the intricacies of coagulation and thrombosis. NINGBO INNO PHARMCHEM CO.,LTD.'s commitment to providing high-purity Apixaban API supports these vital research efforts, contributing to the development of even more advanced anticoagulant therapies.
In summary, Apixaban (CAS 503612-47-3) possesses a robust pharmacological profile that underpins its critical role in managing cardiovascular and thrombotic conditions. Its mechanism as a Factor Xa inhibitor is key to its success, and its availability through reliable suppliers like NINGBO INNO PHARMCHEM CO.,LTD. ensures its continued impact on global health and pharmaceutical innovation.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
