For researchers in fields such as biology, chemistry, and medicine, having access to reliable reagents is fundamental to experimental success. Phloxine B (CAS 18472-87-2) is one such chemical that finds broad utility, particularly in staining and diagnostic applications. Understanding its properties and how to procure it effectively is crucial for scientists and lab managers.

Phloxine B, also known by its synonyms like Acid Red 92 or Cyanosine, is a fluorescent xanthene dye. Its chemical structure, Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one,2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxy-, sodium salt (1:2), with the formula C20H2Br4Cl4Na2O5, highlights its complex halogenated nature. This complexity contributes to its specific spectral properties, making it effective for various staining techniques in histology, cytology, and microbiology, where it helps differentiate cellular components. Scientists often rely on its consistency to ensure reproducible results.

Beyond its staining capabilities, Phloxine B also serves as a valuable tool in biochemical research. It has been noted for its inhibitory effects on certain enzymes, such as UDP-glucuronosyltransferase (UGT) and poly(ADP-ribose) glycohydrolase (PARG), and its interaction with ion channels like the cystic fibrosis transmembrane conductance regulator (CFTR). These properties make it an important chemical for studies investigating cellular pathways and drug mechanisms. When purchasing Phloxine B for research, scientists must ensure the purity meets the demands of their specific experiments.

For researchers looking to buy Phloxine B, several factors should be considered when selecting a supplier. Firstly, the source of the chemical is important; reputable manufacturers and distributors that provide lot-specific Certificates of Analysis (CoA) with purity data (e.g., dye content) are preferred. Secondly, consider the quantity needed. While small research quantities are common, the ability to scale up to bulk purchases from the same supplier can be advantageous for longer-term projects or larger laboratory groups.

The price of Phloxine B can vary depending on the supplier and the quantity purchased. Engaging with manufacturers or their authorized distributors in regions like China can often provide more competitive pricing without compromising on quality, provided thorough due diligence is performed. Ensuring timely delivery is also critical for maintaining research momentum. Therefore, when you need to purchase Phloxine B, choose a supplier that offers both quality assurance and reliable service to support your scientific endeavors.