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Piperlongumine (CAS 20069-09-4): Mechanisms of Action and Supplier Information

Piperlongumine (CAS 20069-09-4) is a natural alkaloid that has garnered significant scientific interest due to its potent biological activities, particularly its anti-cancer effects. Understanding the intricate mechanisms by which this compound operates is vital for researchers aiming to harness its therapeutic potential. As a dedicated Piperlongumine supplier, we provide high-quality material to facilitate these critical investigations.

The primary mechanism of action attributed to Piperlongumine involves its ability to induce oxidative stress within cancer cells. It effectively increases the production of reactive oxygen species (ROS), which can lead to cellular damage, DNA fragmentation, and ultimately, apoptosis (programmed cell death). This targeted induction of cell death is a cornerstone of many modern cancer treatment strategies. Furthermore, research indicates that Piperlongumine can also affect key cellular pathways, such as the androgen receptor signaling in prostate cancer cells, and suppress transcription factors like Sp1 and Sp3, which are often overexpressed in various cancers.

The significance of these cellular effects cannot be overstated for researchers looking to buy Piperlongumine. The compound's ability to selectively target cancer cells, often with minimal impact on normal cells, makes it an attractive candidate for drug development. For entities seeking reliable sourcing, it is crucial to partner with a Piperlongumine manufacturer that can guarantee high purity (typically >97%) and consistent quality. This ensures that experimental results are reproducible and that the compound's biological activity is not compromised by impurities.

When evaluating the Piperlongumine price, consider the value delivered in terms of purity, research support, and supply chain reliability. Sourcing from a reputable Piperlongumine supplier in China or other established regions ensures that you receive a product that meets stringent quality standards. Our commitment as a manufacturer is to provide researchers with the tools they need to advance their studies, whether in understanding cellular mechanisms or developing new therapeutic agents.

The versatility of Piperlongumine extends to its solubility, often being soluble in DMSO, which allows for easy incorporation into various experimental setups. Researchers can confidently use our supplied Piperlongumine for in vitro cell culture studies, mechanism of action investigations, and preclinical in vivo models. We are committed to supporting the scientific community by providing this crucial compound with the quality and reliability necessary for impactful research.

In essence, Piperlongumine (CAS 20069-09-4) represents a powerful natural compound with significant therapeutic implications in oncology. Its complex mechanisms of action, centered around oxidative stress induction and apoptosis, position it as a key player in future cancer therapies. We invite you to contact us to inquire about obtaining this essential research chemical and to discuss how our high-quality Piperlongumine can support your groundbreaking work.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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