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Polyethylene Glycol 4000 (PEG 4000): Key Pharmaceutical Excipient Uses

NINGBO INNO PHARMCHEM CO.,LTD. Presents: Polyethylene Glycol 4000 (PEG 4000)
Polyethylene Glycol 4000, commonly known as PEG 4000, is a highly versatile and widely utilized pharmaceutical excipient. As a solid form, typically available as white or almost white flakes or powder, PEG 4000 plays a crucial role in the formulation and production of a wide range of pharmaceutical preparations.

This grade of Polyethylene Glycol is valued for its excellent physical properties and compatibility with various active pharmaceutical ingredients (APIs). Meeting stringent standards such as USP and EP standards, PEG 4000 ensures reliability and quality in pharmaceutical applications. Its high purity, typically exceeding 99%, and controlled molecular weight range make it a preferred choice for formulators seeking consistent performance.

One of the primary applications of PEG 4000 is its use as a tablet binder in the manufacturing of solid dosage forms. Its unique plasticity during processing helps to create tablets with improved integrity and desired dissolution profiles. By enhancing the release characteristics of drugs from the tablet matrix, PEG 4000 contributes significantly to the efficacy of the final dosage form. Furthermore, it assists in achieving a shiny and smooth tablet surface while reducing the risk of damage during handling and packaging. A small amount is also effective in preventing sticking between icing tablets and preventing adhesion to packaging materials like bottles.

Beyond tablet binding, PEG 4000 serves as a valuable component in other pharmaceutical formats. It is frequently used as an ointment base or bulk material, providing the desired consistency and drug delivery properties for topical formulations. Its lubricating properties also make it useful in various formulations, contributing to processing ease and product performance. Additionally, PEG 4000 finds application in the production of capsules and other solid dosage forms, contributing to their stability and performance characteristics.

The quality of Polyethylene Glycol 4000 is paramount for pharmaceutical use. Reputable suppliers ensure low levels of potential impurities such as formaldehyde, dioxane, and ethylene glycol, meeting rigorous quality control standards for heavy metals and other residues. Proper handling and storage in a cool, dry environment, protected against humidity and pressing, are recommended to maintain its quality and efficacy over its expected shelf life of approximately two years.

For pharmaceutical manufacturers seeking a reliable source of high-quality excipients, understanding the supply chain is essential. Finding a dependable PEG 4000 manufacturer and PEG 4000 supplier is key to ensuring consistent production and product quality. Information regarding PEG 4000 price and availability can be readily obtained from established and experienced suppliers in the market. Those looking to buy PEG 4000 or purchase PEG 4000 in bulk quantities for pharmaceutical applications should connect directly with providers offering pharma-grade material backed by relevant certifications.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

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  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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